Protein Alignment mys and itgb5

DIOPT Version :10

• Sequence 1: NP_524793.2
• Gene: mys / 44885
• FlyBaseID: FBgn0004657
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_001076305.1
• Gene: itgb5 / 563556
• ZFINID: ZDB-GENE-030131-6022
• Length: 823
• Species: Danio rerio
• Alignment Length: 844
• Identity: 311/844 - (36%)
• Similarity: 451/844 - (53%)
• Gaps: 94/844 - (11%)

  Fly    12 ALLMIAILAAIAGQTDAQKAAKLTAVSTCASKEKCHTCIQTE-GCAWCMQPDFKGQ-----SRC- 69
            |||:..:|....      .:.|...|....|...|..|:... .||||.|.|| ||     |||
Zfish    33 ALLVCIVLEIFI------HSVKGLNVCMSGSATSCEECLLIHPSCAWCAQEDF-GQARTLTSRCD 90

  Fly    70 -YQNTSSL-CPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSSSFY 132
             .||.... |...|..:|                            .||||             .
Zfish    91 FSQNLQKRGCDAPFIENP----------------------------RSGSS-------------V 114

  Fly   133 SQSSSGSSSASGYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLSKSM 197
            .||...|...||..:|   :::||.||.:.|:||..::.:.::.....|.||||||||||||.||
Zfish   115 LQSKPLSYKGSGVTQY---DVIQIYPQKISLSLRPGDQASFEVQVRPVEDYPVDLYYLMDLSLSM 176

  Fly   198 EDDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPCE------NCKAPY 256
            :||...:..||.||:|.|:::|:||.|||||||||.:.|:..|..|..::||.      ||...:
Zfish   177 KDDLDTIRNLGTKLAEEMRKLTSNFRLGFGSFVDKNISPFSYTASKYQDNPCNGYKLFPNCVPTF 241

  Fly   257 GYQNHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAG 321
            |:::.:.|.:..:.|:.||:...||.|.||||||||||:||..||.:||||::|..||||:||..
Zfish   242 GFRHLLSLTDKVDRFNEEVQKQMVSRNRDAPEGGFDAILQAAVCREKIGWRKEAYHLLVFATDDV 306

  Fly   322 FHYAGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVY 386
            .|.|.||||||::.|:||:|||:.|.||:.||..||||::.:.:|:.:|.|.:||||......:|
Zfish   307 PHLALDGKLGGLVHPHDGQCHLNDKNEYSASTKMDYPSLALLGEKLAENNIFLIFAVIKRHYVLY 371

  Fly   387 EKLVEHIQGSSAAKLDNDSSNVVELVKEEYRKISSSVEMK--DNATGDVKITYFSSCLSNGPEVQ 449
            :.|...|.|::...||.||.|:::|:...|..|.|.||:.  |:.. |:.:.:.::|....|...
Zfish   372 KNLTALIPGTTVEILDQDSKNIIQLIVNAYNNIRSKVELSVWDHPE-DLSLAFSATCQDGQPLTG 435

  Fly   450 TSKCDNLKEGQQVSFTAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCENPGSIG 514
            ..||.:||.|..|||...:....||  |:...::..|.|||..:.:::.:...|.|.|.
Zfish   436 LRKCADLKIGDTVSFNVTVDARGCP--PKGTRKSFTIRPVGFKDRLEVSVDYRCDCRCT------ 492

  Fly   515 YQVQANS--CSGHGTSMCGICNCDDSYFGNKCECSATDLTSKFANDTSCRADSTSTTDCSGRGHC 577
            |..:.||  |:..||..||:|.|:..|.|.:|||...::..:..  ::|| ::.....|||||.|
Zfish   493 YHTKPNSSRCNSAGTYNCGLCRCEPGYLGARCECQEGEVDHQHL--SACR-EAEGKQVCSGRGEC 554

  Fly   578 VCGACECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGCQE 642
            .|..|.|::  :....|.|..||||:|||.|::..||||  ||.|.||.|||..|:.|.||.|..
Zfish   555 SCNQCLCYE--SEFGKIYGTFCECDDFSCARHKGILCSG--HGECHCGECKCHAGYIGDNCNCST 615

  Fly   643 SNDTCMPPGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQELKDCVQCQMYKTG 707
            ...:|: ...|:||||.|:|.||.|:||  :.|.| |..|||||||...|...::|::|:::.||
Zfish   616 ETASCV-SDDGKICSGRGSCVCGRCQCT--EPGAF-GDTCEKCPTCPDACGTKRECIECRLFNTG 676

  Fly   708 ELKNGDDCARNCTQFVPVGVEKVEIDETKDEQMCKFFDEDDCKFMFKYSE--QGELHVYAQENKE 770
            .|.:...|.|.|...:.. ||.::.|:....| |.:..|:||...|.|||  .|:..:.|.:..|
Zfish   677 RLADNQTCQRMCKDEITT-VETLKTDDPNAVQ-CVYKTENDCVMKFTYSEHANGQSVLTALKEPE 739

  Fly   771 CPAKVFMLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKWDTGENPIYKQA 834
            |......:.:::.|:.:|:|:|:.:|.||||:.|:|||||||||:..|..|:::...||:||::
Zfish   740 CAVAPNAMTVLLAVVGSILLMGIVLLALWKLVITVHDRREFARFQSARSRARYEMASNPVYKRS 803

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mys	NP_524793.2	INB	45..505	CDD:197563	176/476 (37%)
		Integrin_B_tail	692..775	CDD:462325	25/84 (30%)
		Integrin_b_cyt	803..843	CDD:462580	16/32 (50%)
itgb5	NP_001076305.1	INB	60..489	CDD:197563	176/476 (37%)
		I-EGF_1	491..519	CDD:465729	11/33 (33%)
		Integrin_B_tail	661..744	CDD:462325	25/84 (30%)
		Integrin_b_cyt	772..>804	CDD:462580	16/32 (50%)