Protein Alignment mys and itgb2

DIOPT Version :10

• Sequence 1: NP_524793.2
• Gene: mys / 44885
• FlyBaseID: FBgn0004657
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_686012.3
• Gene: itgb2 / 557797
• ZFINID: ZDB-GENE-110411-4
• Length: 768
• Species: Danio rerio
• Alignment Length: 859
• Identity: 300/859 - (34%)
• Similarity: 446/859 - (51%)
• Gaps: 120/859 - (13%)

  Fly     9 CQLALLMIAILAAIAGQTDAQKAAKLTAVSTCASKEKCHTCIQT-EGCAWCMQPDF-----KGQS 67
            |..:||::.:...:..|....||    :|:||..      ||:: .|||||.:.:|     :..:
Zfish     6 CLKSLLLLLVGTQVYTQEQCLKA----SVNTCGD------CIKSGPGCAWCKELNFTKTGEQEAA 60

  Fly    68 RCYQNTSSL-----CPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSS 127
            ||  :|..|     |.:|...:|..:.|.:||..|.
Zfish    61 RC--DTVKLLLDRGCSKENIINPQNIFQNVVNKALV----------------------------- 94

  Fly   128 SSSFYSQSSSGSSSASGYEEYSAG-EIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLM 191
                                  || :.||||||.::|.||.......::.:.:||||||||||||
Zfish    95 ----------------------AGKDPVQIQPQEIQLNLRPGMPQTFQLRFKRAEGYPVDLYYLM 137

  Fly   192 DLSKSMEDDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPC----ENC 252
            |||.||:||.|.:..||:.:.|.:.|||.|..:||||||||.|:||..|...||:|||    |.|
Zfish   138 DLSYSMKDDLANVKNLGNDILEKLNRITGNARIGFGSFVDKTLLPYTDTNEAKLKHPCSDKNEPC 202

  Fly   253 KAPYGYQNHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFS 317
            :..:|:|:.:||..|...|...||...:|||||.|||..||||||..|..:||| ..:.||||.:
Zfish   203 QPAFGFQHVLPLTANGNDFKELVKQQHISGNLDPPEGSLDAIMQAAVCLKEIGW-GNSTRLLVLA 266

  Fly   318 TDAGFHYAGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQ 382
            ||.|||.||||||..::.||...|.|. |.:|:.|.:.||||:.|:.:|:::..|..|||||...
Zfish   267 TDDGFHMAGDGKLAAILEPNKETCQLD-KNKYSKSNIWDYPSVGQVARKLEEQNIQPIFAVTKKM 330

  Fly   383 LSVYEKLVEHIQGSSAAKLDNDSSNVVELVKEEYRKISSSVEMKDNATGD-VKITYFSSCLSNGP 446
            .:||.:|.:.|..|:...|..||:|||.|:.|.|..::|.|.|..:|..: :.:.|.|.|.....
Zfish   331 ETVYTELSKLIPKSAVGVLSEDSNNVVNLIVEAYNNLTSEVIMAHDALPNFISVKYSSKCTGGKT 395

  Fly   447 EVQTSKCDNLKEGQQVSFTAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCENPG 511
            .....||||:..|.:|.|...:.:.:|..|     |:..|.|:|.||.:::.:..||.|.|.:|.
Zfish   396 FSDNGKCDNVNIGLEVIFDVTVTVDRCIND-----QSFSIGPLGFNEKLKVNVQTLCECNCGDPP 455

  Fly   512 SIGYQVQANSCSGHGTSMCGICNCDDSYFGNKCECS--ATDLTSKFANDTSCRADSTSTTDCSGR 574
            .:     ...|.|.|..:||.|.|:|.:.|..|||:  ..|..|..|   .||.|  :.|:|.|:
Zfish   456 GV-----HPHCKGQGKVVCGSCKCNDGFIGQLCECTIGKKDEASFKA---QCRKD--NGTECEGK 510

  Fly   575 GHCVCGACECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCG 639
            |.||||.|:||......... |:|||||:..||:..|:.|:|  ||.|:||:|:|..|:.|:.|.
Zfish   511 GDCVCGRCQCHLTEGNGHFY-GEHCECDDEHCEKFDNKQCAG--HGKCKCGKCECDDGYEGTACH 572

  Fly   640 CQESNDTCMPPGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQELKDCVQCQMY 704
            |.:|::.|..  ...:|...|.|.|..|:|   ::| :.|.:|:.||||...||:...||:|..:
Zfish   573 CAKSDNECKI--DSHVCYNRGKCVCNQCEC---ERG-YKGPYCKTCPTCQRPCQQSGSCVECFAF 631

  Fly   705 KTGELKNGDDCARNCTQFVPVGVEKVEIDETKDEQMCKFFDEDDCKFMFKYSEQGELHVYA---Q 766
            ::|..:.  :|:..|.......|:|:    .|.:  |:..|::.|...|..:|:....:|:   .
Zfish   632 QSGPFEK--NCSLACKHLTIKIVDKL----VKSD--CRVKDKEGCWMAFTMTEELGFDLYSVSVL 688

  Fly   767 ENKECPAKVFMLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKWDTGENPIY 831
            :::|||....::.||.|.:|.:.|:||.:||:.|.:....|.||:.||||:|.:.| .:|.||::
Zfish   689 KDRECPEGPNIIAIVGGSLAGVALIGLLMLLIIKGVLYASDLREWRRFEKDRKHEK-TSGTNPLF 752

  Fly   832 KQATSTFKNPMYAG 845
            :.||:|.:||.::|
Zfish   753 QNATTTVQNPTFSG 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mys	NP_524793.2	INB	45..505	CDD:197563	174/476 (37%)
		Integrin_B_tail	692..775	CDD:462325	20/85 (24%)
		Integrin_b_cyt	803..843	CDD:462580	17/39 (44%)
itgb2	XP_686012.3	vWFA	32..449	CDD:469594	176/482 (37%)
		Integrin_B_tail	619..697	CDD:462325	20/85 (24%)
		Integrin_b_cyt	725..764	CDD:462580	17/39 (44%)