Protein Alignment mys and itgb8

DIOPT Version :10

• Sequence 1: NP_524793.2
• Gene: mys / 44885
• FlyBaseID: FBgn0004657
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_073787461.1
• Gene: itgb8 / 556752
• ZFINID: ZDB-GENE-071213-3
• Length: 779
• Species: Danio rerio
• Alignment Length: 860
• Identity: 259/860 - (30%)
• Similarity: 398/860 - (46%)
• Gaps: 153/860 - (17%)

  Fly    10 QLALLMIAILAAIAGQTDAQKAAKLTAVSTCASKEKCHTCIQT-EGCAWCMQPDFKGQSRCYQNT 73
            ::.||:|::|..:.....|........:||      |..|::. ..||||.|..|...:...|..
Zfish    15 RMLLLLISVLLLLVRSNSADNRCLSALIST------CEDCLRRGPECAWCSQERFLDGAHVSQRC 73

  Fly    74 SSL-------CPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSSSF 131
            .|:       |.|||..:|              :.|.|:             :::.|||
Zfish    74 GSVSDLRVRGCEEEFIENP--------------KVKVEV-------------NATISSS------ 105

  Fly   132 YSQSSSGSSSASGYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLSKS 196
                                   |:.|:.:.:.||...:.:..|...|.|.||||||||:|:|.|
Zfish   106 -----------------------QVAPREITIHLRPGSEASFVIEVQQLERYPVDLYYLVDVSAS 147

  Fly   197 MEDDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPCE----NCKAPYG 257
            |:|:..:|.|:|..||..||:.:::|.:||||||||.:.||:...|.||.:||.    :|:..:|
Zfish   148 MQDNLDRLKTVGLALSHQMKQHSSDFRVGFGSFVDKPVSPYIDVHPSKLLNPCSEYEVHCRPAHG 212

  Fly   258 YQNHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAGF 322
            :.:.:|:..|...|:..::...:|||:|.|||||||::||..|:..||||.:|:.||:..||...
Zfish   213 FIHVLPVTQNMSEFTRVIQEQRISGNMDTPEGGFDAMLQATVCQKDIGWRPEAKHLLLVMTDQPS 277

  Fly   323 HYAGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVYE 387
            |.|.|.||.|::.|:||.|||. ...|:.::..::|:::|:.:|:.:|:|..||||...|...||
Zfish   278 HLALDSKLAGIVVPHDGRCHLE-DNVYSQTSTMEHPTVAQLAEKLLENSIYSIFAVDHLQYQWYE 341

  Fly   388 KLVEHIQGSSAAKLDNDSSNVVELVKEEYRKISSSVEMKDNATGDVKITYF-----SSCLSNGPE 447
            .||:.|.||...:|...:||:.:||.:.|:|:.|.||::.......:...|     :.|......
Zfish   342 DLVDLIPGSYVGRLFPKASNLKDLVVQAYKKLLSDVEVQMELQDPQQAERFWVNVSAICPGGSSA 406

  Fly   448 VQTSKCDNLKEGQQVSFTAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCENPGS 512
            ...|||..::..|.|.|...:.:|.||....|....:.:.|||.||.:::::..||...|.:|
Zfish   407 AGNSKCSGVQPKQTVFFQLTVGMLSCPAGSADQDVLMLVRPVGFNESVRVRIRQLCGSGCTDP-- 469

  Fly   513 IGYQVQANSCSGHGTSMCGICNCDDSYFGNKCECSATDLTSKFANDTSCRADSTSTTDCSGRGHC 577
               :.:.:||:                      .:|:|         ||| :..:|..||.||.|
Zfish   470 ---KPEPSSCT----------------------TNASD---------SCR-EHRNTPVCSSRGVC 499

  Fly   578 VCGACECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGCQE 642
            .||.|.|..  :....|.||.||.|:|||..:...:|.|  ||.|..|.|.|..||||..|.|:|
Zfish   500 RCGTCVCDS--SRFGNIYGKFCEMDDFSCPYDGGLVCGG--HGRCVRGECVCFSGWTGEACACRE 560

  Fly   643 SNDTCMPPGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQELKDCVQCQMYKTG 707
            |.|:|: ...|.||...|.|.||.|.|   |..|.||..|||||.|...||...:||.|
Zfish   561 STDSCV-SDDGFICGDRGRCVCGKCVC---DDPRRSGAFCEKCPMCHSSCQSHWNCVNC------ 615

  Fly   708 ELKN--GDDCARNCTQFVPVGVEKV-EIDETKDEQMCKFFDEDDCKFMFKY---SEQGELH---- 762
            .|.|  |.|..:.|.|.....|:.| :|.|....:.|.:...|.|::.|..   |:..:||
Zfish   616 HLSNGLGSDGFQLCNQSCSPLVDYVDDITELVRGKYCLYPSTDKCQYRFLMELASDGAQLHISRH 680

  Fly   763 ---VYAQENKECPAKVFMLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKWD 824
               |:::...:....||:|.:.:|:   .:|.|:..||      .:..|...::.|.:..:...|
Zfish   681 PVCVWSRRYFKTFLSVFLLTVTLGI---GMLAGVRQLL------RVTGRSCISKTEPQFEHTHKD 736

  Fly   825 TGENPIYKQATSTFK 839
            :...|...:.|.|::
Zfish   737 SSYVPTSSEKTITYR 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mys	NP_524793.2	INB	45..505	CDD:197563	150/476 (32%)
		Integrin_B_tail	692..775	CDD:462325	23/95 (24%)
		Integrin_b_cyt	803..843	CDD:462580	6/37 (16%)
itgb8	XP_073787461.1	None