Protein Alignment mys and Itgb5

DIOPT Version :10

• Sequence 1: NP_524793.2
• Gene: mys / 44885
• FlyBaseID: FBgn0004657
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_671480.2
• Gene: Itgb5 / 257645
• RGDID: 628869
• Length: 799
• Species: Rattus norvegicus
• Alignment Length: 846
• Identity: 310/846 - (36%)
• Similarity: 449/846 - (53%)
• Gaps: 93/846 - (10%)

  Fly     9 CQLALLMIAILAAIAGQTDAQKAAKLTAVSTCASKEKCHTCIQTE-GCAWCMQPDFKGQ----SR 68
            |.|.|  .|::..:||..          :.|..|...|..|:... .||||.:..|...    ||
  Rat    11 CLLGL--CALVPRLAGLN----------ICTSGSATSCEECLLIHPKCAWCSKEYFGNPRSIISR 63

  Fly    69 CYQNTSSLCPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSSSFYS 133
            |                              ..||.|...|.|..:...:||::...:...|...
  Rat    64 C------------------------------DLKANLIRNGCGGEIESPASSTHVLRNLPLSSKG 98

  Fly   134 QSSSGSSSASGYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLSKSME 198
            .|:.||            :::|:.||.:.::||..::...::...|.|.||||||||||||.||:
  Rat    99 SSAMGS------------DVIQMTPQEIAVSLRPGDQATFQLQVRQVEDYPVDLYYLMDLSLSMK 151

  Fly   199 DDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPC------ENCKAPYG 257
            ||...:.:||.||:|.|:::|:||.|||||||||.:.|:..|.|:...:||      .||...:|
  Rat   152 DDLDNIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFG 216

  Fly   258 YQNHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAGF 322
            :::.:||.:..:||:.||:...||.|.|||||||||::||..|:.:||||:.|..||||:||...
  Rat   217 FRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVP 281

  Fly   323 HYAGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVYE 387
            |.|.||||||::.|:||:|||:...|||.|...||||::.:.:|:.:|.||:|||||.:...:|:
  Rat   282 HIALDGKLGGLVQPHDGQCHLNEANEYTASDQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYK 346

  Fly   388 KLVEHIQGSSAAKLDNDSSNVVELVKEEYRKISSSVEMKD-NATGDVKITYFSSCLSNGPEVQTS 451
            .....|.|::...|..||.|:::|:...|..|.:.||:.. :...|:.:.:.::|..........
  Rat   347 NFTALIPGTTVEILHGDSKNIIQLIINAYSSIRAKVELSVWDQPEDLNLFFTATCQDGLSYPGQR 411

  Fly   452 KCDNLKEGQQVSFTAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCENPGSIGYQ 516
            ||:.||.|...||...::...||  .|..||:..:.|||..:.:|:::...|:|.|    |.|.:
  Rat   412 KCEGLKIGDTASFEVSVEARSCP--GRHTTQSFTLRPVGFRDSLQVEVAYNCTCGC----SAGLE 470

  Fly   517 VQANSCSGHGTSMCGICNCDDSYFGNKCECSATDLTSKFANDTSCRADSTSTTDCSGRGHCVCGA 581
            ..:..|||:||.:||:|.||.||.|.:|||...:..|.:.|  .|| ::.....|||||.|.|..
  Rat   471 PNSARCSGNGTYVCGLCECDPSYLGTRCECQEGENQSGYQN--LCR-EAEGKPLCSGRGECSCNQ 532

  Fly   582 CECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGCQESNDT 646
            |.|.:  :....|.|..||||:|||.||:..||||  ||.|.||.|||..|:.|.||.|.....|
  Rat   533 CSCFE--SEFGRIYGPFCECDSFSCARNKGVLCSG--HGECHCGECKCHVGYIGDNCNCSTDIST 593

  Fly   647 CMPPGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQELKDCVQCQMYKTGELKN 711
            |... .|:|||..|.|.||.|:||  :.|.| |..|||||||...|...:|||:|.:...|:..|
  Rat   594 CRAK-DGQICSDRGRCVCGQCQCT--EPGAF-GETCEKCPTCPDACSSKRDCVECSLLHQGKPDN 654

  Fly   712 GDDCARNCTQFVPVGVEKVEIDETKDEQ---MCKFFDEDDCKFMFKYSE--QGELHVYAQENKEC 771
             ..|...|...|...|:.:    .||:|   :|.:....||..||.|:|  .|:.::......||
  Rat   655 -QTCHHQCKDEVITWVDSI----VKDDQEAVLCFYKTAKDCVMMFSYTELPNGKSNLTVLREPEC 714

  Fly   772 PAKVFMLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKWDTGENPIYKQATS 836
            .:....:.|::.|:.:|:|||:|:|.:||||.|||||||||:|:.||..|:::...||:|::..|
  Rat   715 GSAPNAMTILLAVVGSILLVGMALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPIS 779

  Fly   837 T 837
            |
  Rat   780 T 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mys	NP_524793.2	INB	45..505	CDD:197563	164/471 (35%)
		Integrin_B_tail	692..775	CDD:462325	24/87 (28%)
		Integrin_b_cyt	803..843	CDD:462580	18/35 (51%)
Itgb5	NP_671480.2	INB	35..463	CDD:197563	164/471 (35%)
		I-EGF_1	465..493	CDD:465729	13/31 (42%)
		Nar1	486..>613	CDD:443663	60/134 (45%)
		Integrin_B_tail	635..718	CDD:462325	24/87 (28%)
		Integrin_b_cyt	746..781	CDD:462580	18/35 (51%)