Protein Alignment mys and Itgb7

DIOPT Version :10

• Sequence 1: NP_524793.2
• Gene: mys / 44885
• FlyBaseID: FBgn0004657
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_037303.1
• Gene: Itgb7 / 25713
• RGDID: 2929
• Length: 807
• Species: Rattus norvegicus
• Alignment Length: 849
• Identity: 309/849 - (36%)
• Similarity: 444/849 - (52%)
• Gaps: 110/849 - (12%)

  Fly    23 AGQTDAQKAAKLTAVSTCASKEKCHTCIQTE-GCAWCMQPDF--KGQS---RCYQNTSSL---CP 78
            :|:|...:...|:...:|.....|..||.:. .||||.|.:|  .|::   ||.:....|   ||
  Rat    28 SGETTEWEDPDLSPQGSCQPAPSCQKCILSHPSCAWCKQLNFTASGEAEARRCARREELLARGCP 92

  Fly    79 EEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSSSFYSQSSSGSSSAS 143
            |:....|...:::|.:..|                                   ||...|..:
  Rat    93 EQELEEPRGHQEVLQDRPL-----------------------------------SQGDRGEGA-- 120

  Fly   144 GYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLSKSMEDDKAKLSTLG 208
                      .|:.||.:|:.||..|....::.:.:|.|||||||||||||.||:||..::..||
  Rat   121 ----------TQLAPQRIRVTLRPGEPQKFRVRFLRAAGYPVDLYYLMDLSYSMKDDLERVRQLG 175

  Fly   209 DKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPC----ENCKAPYGYQNHMPLNNNTE 269
            ..|...::.:|::..:||||||||.::|:|||:|.||.|||    |.|:||:.|.:.:||..:.:
  Rat   176 QALLLRLREVTHSVRIGFGSFVDKTVLPFVSTVPSKLNHPCPSRLERCQAPFSYHHVLPLTRDAQ 240

  Fly   270 SFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAGFHYAGDGKLGGVI 334
            :|..||....||||||:||||||||:||..|:.||||| ...|||||::|..||.||||||||:.
  Rat   241 AFEREVGRQNVSGNLDSPEGGFDAILQAALCQEQIGWR-NVSRLLVFTSDDTFHTAGDGKLGGIF 304

  Fly   335 APNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVYEKLVEHIQGSSAA 399
            .|:||.|||...|.||:|...||||:.|:.|.:....|..|||||.:.|.||::|.:.|..|:..
  Rat   305 MPSDGRCHLDSNGVYTNSAEFDYPSVGQVAQALTAANIQPIFAVTGATLPVYQELSQLIPKSAVG 369

  Fly   400 KLDNDSSNVVELVKEEYRKISSSVEMKDNA-TGDVKITYFSSCLSNGPEV-------QTSKCDNL 456
            :|..||||||:|:.:.|..:||:|.::.:: ...|.|::.|.|.|  ||.       :..:|:::
  Rat   370 ELSEDSSNVVQLIMDAYDNLSSTVTLEHSSLPPGVSISFESHCRS--PEKSEGEAGDRRGQCNHV 432

  Fly   457 KEGQQVSFTAQIQLLKC-PEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCENPGSIGYQVQAN 520
            :..|.|.|...:|...| ||     ...:.:..:|.:|.:.::|..||.|.|.:.     |.:|.
  Rat   433 RVNQMVDFWVTLQASHCLPE-----AHVLRLWALGFSEELTVELHTLCDCNCSDA-----QPRAP 487

  Fly   521 SCS-GHGTSMCGICNCDDSYFGNKCECSATDLTSKFANDTSCRADSTSTTDCSGRGHCVCGACEC 584
            .|| |.|...||||:|.....|..||||..||:|... ::.|||.:.:...|||:|.|.||.|.|
  Rat   488 YCSDGQGDLQCGICSCAPGRLGQLCECSEADLSSPDL-ESGCRAPNGTGPLCSGKGRCQCGRCSC 551

  Fly   585 HKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGCQESNDTCMP 649
            ..:.      ||:.||||:.||||:...||.|  .|.|:||.|.|....||..|.|.||.|:|:.
  Rat   552 SGQS------SGRLCECDDASCERHEGILCGG--FGHCQCGVCHCHANRTGRACECSESVDSCVS 608

  Fly   650 PGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQELKDCVQCQMYKTGELKNGDD 714
            |.|| :|||||.|:|..|:|.    ..:.|..|::|..|...|::.:||.:|..:.||.|  ..:
  Rat   609 PEGG-LCSGHGDCKCNRCQCL----DGYYGALCDQCLGCKSPCEQYRDCAECGAFGTGPL--AAN 666

  Fly   715 CARNCTQFVPVGVEKVEIDETKDEQMCKFFDEDDCKFMF--KYSEQGE-LHVYAQENKECPAKVF 776
            |:..|..   |.| .:.:....|:..||....|:..|.|  :.|.:|. |.|..||......:..
  Rat   667 CSAACAD---VNV-TLALAPNLDDGWCKERTLDNQLFFFLVENSARGVILRVRPQEKGADHTRAI 727

  Fly   777 MLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKWDTGENPIYKQATSTFKNP 841
            :||.|.|::|    |||.::|.::|...::||.|::||||||....|....||:||.|.:|..||
  Rat   728 ILGCVGGIVA----VGLGLVLAYRLSVEVYDRLEYSRFEKERQQLNWKQDSNPLYKSAVTTTVNP 788

  Fly   842 MYAG 845
            .:.|
  Rat   789 RFQG 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mys	NP_524793.2	INB	45..505	CDD:197563	177/481 (37%)
		Integrin_B_tail	692..775	CDD:462325	23/85 (27%)
		Integrin_b_cyt	803..843	CDD:462580	18/39 (46%)
Itgb7	NP_037303.1	INB	50..477	CDD:197563	177/481 (37%)
		I-EGF_1	477..507	CDD:465729	13/34 (38%)
		Integrin_B_tail	646..717	CDD:462325	21/76 (28%)
		Integrin_b_cyt	750..790	CDD:462580	18/39 (46%)