Protein Alignment mys and Itgb7

DIOPT Version :10

• Sequence 1: NP_524793.2
• Gene: mys / 44885
• FlyBaseID: FBgn0004657
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_038594.2
• Gene: Itgb7 / 16421
• MGIID: 96616
• Length: 806
• Species: Mus musculus
• Alignment Length: 873
• Identity: 309/873 - (35%)
• Similarity: 445/873 - (50%)
• Gaps: 129/873 - (14%)

  Fly    14 LMIAILAAIAGQ-------TDAQKAAK-----LTAVSTCASKEKCHTCIQTE-GCAWCMQPDF-- 63
            ::|.:|....||       |.:.:||:     |:...:|.....|..||.:. .||||.|.:|
Mouse     7 VLIFLLVLGGGQSELDTKITSSGEAAEWEDPDLSLQGSCQPVPSCQKCILSHPSCAWCKQLNFTA 71

  Fly    64 KGQS---RCYQNTSSL---CPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSY 122
            .|::   ||.:....|   ||.:....|...:::|.:..|
Mouse    72 SGEAEARRCARREELLARGCPAQELEEPRGRQEVLQDKPL------------------------- 111

  Fly   123 SSSSSSSSFYSQSSSGSSSASGYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDL 187
                      ||...|..:            .|:.||.:|:.||..|....::.:.:|.||||||
Mouse   112 ----------SQGDRGEGA------------TQLAPQRIRVTLRPGEPQKFRVRFLRAAGYPVDL 154

  Fly   188 YYLMDLSKSMEDDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPC--- 249
            |||||||.||:||..::..||..|...::.:|::..:||||||||.::|:|||:|.||.|||
Mouse   155 YYLMDLSYSMKDDLERVRQLGHALLVRLQEVTHSVRIGFGSFVDKTVLPFVSTVPSKLHHPCPSR 219

  Fly   250 -ENCKAPYGYQNHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRL 313
             |.|:.|:.:.:.:.|..:.::|..||....||||||:||||||||:||..|:.||||| ...||
Mouse   220 LERCQPPFSFHHVLSLTGDAQAFEREVGRQNVSGNLDSPEGGFDAILQAALCQEQIGWR-NVSRL 283

  Fly   314 LVFSTDAGFHYAGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAV 378
            |||::|..||.||||||||:..|:||.|||...|.||:|...||||:.|:.|.:....|..||||
Mouse   284 LVFTSDDTFHTAGDGKLGGIFMPSDGRCHLDSNGVYTNSAEFDYPSVGQVAQALTAANIQPIFAV 348

  Fly   379 TASQLSVYEKLVEHIQGSSAAKLDNDSSNVVELVKEEYRKISSSVEMKDN-ATGDVKITYFSSCL 442
            |.:.|.||::|.:.|..|:..:|..||||||:|:.:.|..:||:|.::.: ....|.|::.|.|
Mouse   349 TGATLPVYQELRQLIPKSAVGELSEDSSNVVQLIMDAYDSLSSTVTLEHSPLPPGVSISFESHC- 412

  Fly   443 SNGPEV------QTSKCDNLKEGQQVSFTAQIQLLKC-PEDPRDWTQTIHISPVGINEVMQIQLT 500
             .|||.      ...:|::::..|.|.|...:|...| ||     ...:.:..:|.:|.:.::|.
Mouse   413 -KGPEKTEGEAGDRGQCNDVRVNQTVDFWVTLQATHCLPE-----AHVLRLWALGFSEELTVELH 471

  Fly   501 MLCSCPCENPGSIGYQVQANSCS-GHGTSMCGICNCDDSYFGNKCECSATDLTSKFANDTSCRAD 564
            .:|.|.|.:.     |..|..|| |.|...||||:|.....|..||||..||:|... ::.|||.
Mouse   472 TVCDCNCGDA-----QPHAPYCSDGQGDLQCGICSCAPGRLGQLCECSEADLSSPDL-ESGCRAP 530

  Fly   565 STSTTDCSGRGHCVCGACECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKC 629
            :.:...|||:|.|.||.|.|..:.      ||:.||||:.||||:...||.|  .|.|:||.|.|
Mouse   531 NGTGPLCSGKGRCQCGRCSCSGQS------SGRLCECDDASCERHEGILCGG--FGHCQCGVCHC 587

  Fly   630 KPGWTGSNCGCQESNDTCMPPGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQE 694
            ....||..|.|.:|.|:|:.|.|| :|||||.|:|..|:|.    ..:.|..|::|..|...|::
Mouse   588 HANHTGRACECSKSVDSCVSPEGG-LCSGHGYCKCNRCQCL----DGYYGALCDQCLGCKSPCEQ 647

  Fly   695 LKDCVQCQMYKTGELKNGDDCARNCTQFVPVGVEKVEIDET----KDEQMCKFFDEDDCKFMF-- 753
            .:||.:|..:.||.|      |.||:    |....|.:..|    .|:..||....|:..|.|
Mouse   648 YRDCAECGAFGTGPL------AANCS----VVCADVNVTLTLAPNLDDGWCKERTIDNQLFFFLV 702

  Fly   754 KYSEQG-ELHVYAQENKECPAKVFMLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKE 817
            :::..| .|.|..||......:..:||...|::|    |||.::|.::|...|:||||:.|||||
Mouse   703 EHAASGIVLRVRPQEKGVDHTRAIILGCTGGIVA----VGLGLVLAYRLSVEIYDRREYRRFEKE 763

  Fly   818 RMNAKWDTGENPIYKQATSTFKNPMYAG 845
            :....|....||:||.|.:|..||.:.|
Mouse   764 QQQLNWKQDNNPLYKSAITTTVNPRFQG 791

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mys	NP_524793.2	INB	45..505	CDD:197563	172/480 (36%)
		Integrin_B_tail	692..775	CDD:462325	24/89 (27%)
		Integrin_b_cyt	803..843	CDD:462580	19/39 (49%)
Itgb7	NP_038594.2	INB	50..476	CDD:197563	172/480 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	98..123		6/71 (8%)
		I-EGF_1	476..506	CDD:465729	13/34 (38%)
		EGF_2	612..635	CDD:400365	10/26 (38%)
		Integrin_B_tail	645..716	CDD:462325	22/80 (28%)
		Integrin_b_cyt	749..789	CDD:462580	19/39 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	786..806		3/6 (50%)