Protein Alignment mys and Itgb2

DIOPT Version :9

• Sequence 1: NP_001284997.1
• Gene: mys / 44885
• FlyBaseID: FBgn0004657
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_032430.2
• Gene: Itgb2 / 16414
• MGIID: 96611
• Length: 770
• Species: Mus musculus
• Alignment Length: 859
• Identity: 297/859 - (34%)
• Similarity: 435/859 - (50%)
• Gaps: 127/859 - (14%)

  Fly    17 AILAAIAGQTDAQKAAKLTAVSTCASKE-------KCHTCIQT-EGCAWCMQPDFKGQS-----R 68
            ::|.|:||         |..:.:..|:|       .|..|||: .||:||.:.:|.|..     |
Mouse     6 SLLLALAG---------LFFLGSAVSQECTKYKVSSCRDCIQSGPGCSWCQKLNFTGPGEPDSLR 61

  Fly    69 CYQNTSSL---CPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSSS 130
            |......|   ||.:....|
Mouse    62 CDTRAQLLLKGCPADDIMDP--------------------------------------------- 81

  Fly   131 FYSQSSSGSSSASGYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLSK 195
                     .|.:..|....|:..|:.||.:.|.||..:.....:::.:|:|||:|||||||||.
Mouse    82 ---------RSIANPEFDQRGQRKQLSPQKVTLYLRPGQAAAFNVTFRRAKGYPIDLYYLMDLSY 137

  Fly   196 SMEDDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKNLVEPCAN----CTATY 256
            ||.||...:..||..|.:.:..||.:..:||||||||.::|:|:|.|:.|..||.|    |...:
Mouse   138 SMLDDLNNVKKLGGDLLQALNEITESGRIGFGSFVDKTVLPFVNTHPEKLRNPCPNKEKACQPPF 202

  Fly   257 GFHHQMVLDKNITQFTNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAG 321
            .|.|.:.|..|..||..||....:||||||||||.|||||..||..:|||| ...|||||:||.|
Mouse   203 AFRHVLKLTDNSNQFQTEVGKQLISGNLDAPEGGLDAIMQVAACPEEIGWR-NVTRLLVFATDDG 266

  Fly   322 FHYAGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVY 386
            ||:|||||||.::.||||.|||. ...|..|...||||:.|:..|:.::.|..|||||...:..|
Mouse   267 FHFAGDGKLGAILTPNDGRCHLE-DNMYKRSNEFDYPSVGQLAHKLSESNIQPIFAVTKKMVKTY 330

  Fly   387 EKLVEHIQGSSAAKLDNDSSNVVELVKEEYRKISSSVEMKDNATGD-VKITYFSSCLSNGPEVQT 450
            |||.|.|..|:..:|.:||||||:|:|..|.|:||.|.:..:...| :|:||.|.|.:....:..
Mouse   331 EKLTEIIPKSAVGELSDDSSNVVQLIKNAYYKLSSRVFLDHSTLPDTLKVTYDSFCSNGASSIGK 395

  Fly   451 SK--CDNLKEGQQVSFTAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCENPGSI 513
            |:  ||.::....|:|..::...:|.::     |:..|..:|..:.:.:|:...|.|.|.:...
Mouse   396 SRGDCDGVQINNPVTFQVKVMASECIQE-----QSFVIRALGFTDTVTVQVRPQCECQCRDQSR- 454

  Fly   514 GYQVQANSCSGHGTSMCGICNCDDSYFGNKCECSATDLTSKFANDTSCRADSTSTTDCSGRGHCV 578
                :.:.|.|.|...||||.|:..|.|..|||.....:|: ..:.:||.|::|.. |||.|.|:
Mouse   455 ----EQSLCGGKGVMECGICRCESGYIGKNCECQTQGRSSQ-ELERNCRKDNSSIV-CSGLGDCI 513

  Fly   579 CGACECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGCQES 643
            ||.|.||....|.:.|.|::|||||.:|||..:|:|.|.|.|:|.||:|.||||:.||.|.||.|
Mouse   514 CGQCVCHTSDVPNKEIFGQYCECDNVNCERYNSQVCGGSDRGSCNCGKCSCKPGYEGSACQCQRS 578

  Fly   644 NDTCMPPGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQE-LKDCVQCQMYKTG 707
            ...|:.....| |||.|.|:|..|.|   |:| :....||.||:|...|:: ...|.:|..:..|
Mouse   579 TTGCLNARLVE-CSGRGHCQCNRCIC---DEG-YQPPMCEDCPSCGSHCRDNHTSCAECLKFDKG 638

  Fly   708 ELKNGDDCARNCT----QFVPVGVEKVEIDETKDEQMCKFFDEDDCKFMFKYSEQGELHVY---A 765
            ..:.  :|:..|.    |.:|:           .::.||..|.:.|...:...::...::|   .
Mouse   639 PFEK--NCSVQCAGMTLQTIPL-----------KKKPCKERDSEGCWITYTLQQKDGRNIYNIHV 690

  Fly   766 QENKECPAKVFMLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKWDTGENPI 830
            :::.||.....:..||.|.:..:||:|:.:|::||.||.:.|.||:.|||||::.::|: .:||:
Mouse   691 EDSLECVKGPNVAAIVGGTVVGVVLIGVLLLVIWKALTHLTDLREYRRFEKEKLKSQWN-NDNPL 754

  Fly   831 YKQATSTFKNPMYA 844
            :|.||:|..||.:|
Mouse   755 FKSATTTVMNPKFA 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mys	NP_001284997.1	INB	45..505	CDD:197563	169/475 (36%)
		Integrin_B_tail	692..773	CDD:285239	15/88 (17%)
		Integrin_b_cyt	803..843	CDD:285884	18/39 (46%)
Itgb2	NP_032430.2	Integrin_beta	32..447	CDD:278776	169/475 (36%)
		Cysteine-rich tandem repeats	449..617		74/179 (41%)
		Integrin_B_tail	626..700	CDD:285239	14/86 (16%)
		Integrin_b_cyt	727..767	CDD:285884	19/40 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	261	1.000	Domainoid score	I1946
eggNOG	1	0.900	-	-		E1_KOG1226
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	647	1.000	Inparanoid score	I792
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48224
OrthoDB	1	1.010	-	-		D223415at33208
OrthoFinder	1	1.000	-	-		FOG0001086
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100678
Panther	1	1.100	-	-	O	PTHR10082
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X739
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.840