Protein Alignment mys and itgb8

DIOPT Version :10

• Sequence 1: NP_524793.2
• Gene: mys / 44885
• FlyBaseID: FBgn0004657
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_002933344.3
• Gene: itgb8 / 100494899
• XenbaseID: XB-GENE-950732
• Length: 808
• Species: Xenopus tropicalis
• Alignment Length: 861
• Identity: 247/861 - (28%)
• Similarity: 378/861 - (43%)
• Gaps: 182/861 - (21%)

  Fly     8 RCQLALL-MIAILAAIAGQTDA-QKAAKLTAVSTCASKEKCHTCIQTEGCAWCMQPDFKGQS--- 67
            ||.:::| ...:|..:.|...: :.....::.:|||   || ..:..| |.||.|.||...|
 Frog    69 RCFMSILRAFGLLFLLLGLCQSVENRCSSSSATTCA---KC-LALGPE-CGWCTQEDFMMDSTEN 128

  Fly    68 -RCYQNTSSLCPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSSSF 131
             ||                                         .:|::..|......|....:.
 Frog   129 ERC-----------------------------------------DTALNLKSKGCRQDSIEYPTA 152

  Fly   132 YSQSSSGSSSASGYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLSKS 196
            ::|..|...:.|           |:.|..:.:.:|...|.|..:.......||:|:|||:|:|.|
 Frog   153 HAQPLSSRDTNS-----------QVTPAEVSVHIRPGAKVNFMLKVHHLRKYPLDIYYLVDISAS 206

  Fly   197 MEDDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPCE----NCKAPYG 257
            |....|:|:::|..||:.|...:::...||||||||.:.||:|..|:|:::.|.    .|..|:|
 Frog   207 MHKSIARLNSVGFDLSQKMANFSDDIKYGFGSFVDKPVSPYISVHPQKIKNQCSVVDLVCMPPHG 271

  Fly   258 YQNHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAGF 322
            |.|.:||..||..|.|.|....::||:|.|||.|:|::||..|.:.||||::||.||:..||...
 Frog   272 YINVLPLTYNTTKFKNVVGKQRIAGNIDNPEGAFEAMLQAAVCNTDIGWRKEARHLLILMTDQTS 336

  Fly   323 HYAGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVYE 387
            |.|.|.||.|::.||||.|||. ...|..|:..:|||:..:.:|:.:|.|:.:|||...|.:.|:
 Frog   337 HLALDSKLAGIVTPNDGSCHLK-DNVYIRSSDMEYPSLGLLGEKLTENHISGVFAVQGPQFNWYK 400

  Fly   388 KLVEHIQGSSAAKLDNDSSNVVELVKEEYRKISSSVEMK-DNATGDVKITYFSSCLSNGPEVQTS 451
            .|:..|.|::|.:||..:||:..||.:.|:.:.|.|::: ||....:.:...:.|..........
 Frog   401 DLLPLIPGTTARQLDPFASNMKNLVFDAYKMLLSEVKIEVDNPIKGIHVHVTAICPDGTRRSGKE 465

  Fly   452 KCDNLKEGQQVSFTAQIQLLKCP-EDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCENPGSIGY 515
            .|.|:|..::|.|...:.:..|. .:.||:   |.:.|:|.||...|::...|:|.|
 Frog   466 GCQNVKANEKVFFNVTLTMDSCDVHNGRDY---IVLRPLGFNETAIIKVHRDCTCQC-------- 519

  Fly   516 QVQANSCSGHGTSMCGICNCDDSYFGNKCE--------CSATDLTSKFANDTSCRADSTSTTDCS 572
                ||.|    ...|.|..|||   ..|:        ||:.:|.|.   ..|||| |.|...||
 Frog   520 ----NSVS----QAKGKCVTDDS---TDCQTTPCKEEICSSDELDSA---SESCRA-SPSQPVCS 569

  Fly   573 GRGHCVCGACECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSN 637
            |||.|:||.|.|.|  ..:..|.||:||.|.|||..:..:||||  :|.||.|:|:|..||....
 Frog   570 GRGVCLCGKCFCQK--TKLGAIYGKYCEKDTFSCPYHHGKLCSG--NGDCEDGKCRCFNGWESDR 630

  Fly   638 CGCQES-NDTCMPPGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQELKDCV-- 699
            |.|..| ...|| ...|.:|||.|.|:||.|:||  |...| |..|:.| |.:..|:..:...
 Frog   631 CHCASSLRKHCM-NSKGLVCSGRGVCQCGKCECT--DAKSF-GPLCQYC-TDNWNCEHFQGSANV 690

  Fly   700 ---QCQMYKTGELKNGDDCARNCTQFVPVGVEKVEIDETKDEQMCKFFDEDDCKFMFKYSEQGEL 761
               :..:|:|.       ||.                                           |
 Frog   691 SEPEGNLYETA-------CAL-------------------------------------------L 705

  Fly   762 HVYAQENKEC--PAKVFMLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKWD 824
            ..|..:..||  ..::..|..::.::.  .|:|:..:||.:.:...|.:      .::|....:.
 Frog   706 VYYIDQTSECFSDPRILTLFFIISIVT--FLLGILTVLLTRHIILHHHK------TRDRSTPSYR 762

  Fly   825 TGENPIYKQATSTFKN 840
            |   |..|:..|...|
 Frog   763 T---PTNKKDKSVLHN 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mys	NP_524793.2	INB	45..505	CDD:197563	143/469 (30%)
		Integrin_B_tail	692..775	CDD:462325	9/89 (10%)
		Integrin_b_cyt	803..843	CDD:462580	7/38 (18%)
itgb8	XP_002933344.3	vWFA	102..517	CDD:469594	146/475 (31%)