back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rhi and Mphosph8

DIOPT Version :10

Sequence 1:	NP_536794.1	Gene:	rhi / 44879	FlyBaseID:	FBgn0004400	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001347001.1	Gene:	Mphosph8 / 75339	MGIID:	1922589	Length:	870	Species:	Mus musculus

Alignment Length:	434	Identity:	91/434 - (20%)
Similarity:	158/434 - (36%)	Gaps:	135/434 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 DHVEEYVVEKILGKRFVNGRPQVLVKWSGFPNENNTWEPLENVGNCMKLVSDFESEVFRLHRKAA 83
            |..:.:.||:||..:...|:....|:|.|:.:|::||||..::.:|.:::.:|..::.....||.
Mouse    54 DGEDVFEVERILDMKCEGGKNLYKVRWKGYTSEDDTWEPEVHLEDCKEVLLEFRKKLAENKAKAV 118

  Fly    84 AKSVGK-----------SKSSPSSSGPLITENGPSSSKKTQQHSKSVQAKNTAGMSKMNQKKGKN 137
            .|.:.:           |.|...|.    |:...|..||    .|.::.|.......:.:|:.|
Mouse   119 RKDIQRLSLNNDIFEADSDSDQQSD----TKEDISPRKK----KKKIKCKEETSPEDLRKKRTK- 174

  Fly   138 IKKTAGKIKDIENYPKTQMPSTSQVSTDSTEVFDGNPSATTTNMI----------KSPRIQSLFS 192
                .||:||   ..||::.|||::..     ||    ..|...|          |.|:...:..
Mouse   175 ----MGKLKD---KFKTELESTSEIIG-----FD----VKTKKRIWEVKEELKDSKKPKKDEIKE 223

  Fly   193 DLNLIEPTKDKDVGDTSLK--------TPPKSRRLIEFPQREDAPLSSKHVSPMLIRKESQPLQS 249
            ...|.:..|..:|.|..:|        ...|..|.||.|...::|..|     :::..:|:...|
Mouse   224 TKELKKANKRAEVRDLKIKIREDVKENRKTKKERYIESPLESESPNDS-----LILEDDSEDFIS 283

  Fly   250 SCTDDSDLGESSSSMSLPTVSSTSSE-----------------------KSIKVTK-SEPKTLGQ 290
               |:.:..::..|:...|...|..|                       |..|..| .|||.:.:
Mouse   284 ---DNREENQNVRSVRDKTAQETVQEGIFEKHLDDLISIEEDAGTRVRRKKTKPRKFEEPKEIKK 345

  Fly   291 IKFSS------------RSSDGGHA------------ASSLGAPKEGDIGLDLSGSD-SMDSE-- 328
            ::.::            |:.|.|.:            |.:|.:.:       |||.: |:.|.
Mouse   346 LESTNAFLERRAIPKKQRNQDKGISNLELNKLPSPVFAQTLKSSR-------LSGEEKSLKSPDL 403

  Fly   329 ------VESMRRCPRRKRKKTYPDWKFPEMTKPFGVNRGLDLDK 366
                  ||:::.....|.||..|..|:         .:..||||
Mouse   404 AEEVKLVENLKSTDMEKEKKNEPKGKY---------QKRYDLDK 438

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.