DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment rhi and cbx4

DIOPT Version :9

Sequence 1:NP_536794.1 Gene:rhi / 44879 FlyBaseID:FBgn0004400 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_991312.1 Gene:cbx4 / 573110 ZFINID:ZDB-GENE-040329-2 Length:477 Species:Danio rerio


Alignment Length:470 Identity:109/470 - (23%)
Similarity:164/470 - (34%) Gaps:162/470 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 DHVEEYVVEKILGKRFVNGRPQVLVKWSGFPNENNTWEPLENVGNCMKLVSDFESEVFRLHRKAA 83
            :||  :.||.|..||...||.:.||||.|:..:.|||||.||:.:...||: |:      :|:..
Zfish     8 EHV--FAVEGIEKKRLRKGRMEYLVKWRGWSPKYNTWEPEENILDPRLLVA-FQ------NRERQ 63

  Fly    84 AKSVGKSKSSPSSSGPLI---------------------TENGPS----------------SSKK 111
            .:.||..|..|....|||                     .||.|.                :|||
Zfish    64 EQMVGYRKRGPKPKHPLIQLPAFARRSSILGGLQDTSLDEENQPKVDSLQMHRSRPQHYQLNSKK 128

  Fly   112 TQQHSKSVQ----AKNTAGMSK----MNQKKGKNIKKTAGKIKDIENYPKTQMPSTSQVSTDSTE 168
            ..|:..|.:    .::.:|..|    :|.||..:.:            |..:|..|.  .|...|
Zfish   129 HHQYQPSCKEISVEQHMSGKKKHFYQLNSKKHHHYQ------------PDPKMYDTP--LTGPKE 179

  Fly   169 VFDGNPSATTTNMIKSPRIQSLF---SDLNLIEPTKDKDVGDTSLKTPP----KSRRLIEFPQRE 226
            |...:||....|:  .|.:|..:   .|...:...||..:   .||..|    |:.|.::...:|
Zfish   180 VKGQDPSNKGWNL--PPALQQKWIRNKDTGCLSKVKDLSI---ELKGLPDNANKAERTLKTSAKE 239

  Fly   227 DA---PLSSK-------------------------HVSPM---------LIRKESQPLQSSCTDD 254
            .|   .:|||                         |.|.:         .:..|..|:..  ||:
Zfish   240 FALPNGISSKMKIIKNKNKNGRIVIVMSKYMDKGVHSSKVKNRDVSQVGTVHNEEPPVNG--TDN 302

  Fly   255 ------SDLGESSSSMSLPTVSSTSSEKSIKVTKSEPKTLGQ-------------IKFSSRSSDG 300
                  .|.||...:.|:...|....|||::  |..|   ||             .|..::|:  
Zfish   303 RSDGETPDQGEGRENGSIEKPSEYVDEKSLR--KDMP---GQKATEICDRPNSSPAKVDAKSN-- 360

  Fly   301 GHAASSLGAPKEGDIG--LDLSGSDSMDSEVESMRRCPRRKRKKTYP--DWKF----PEMTKPFG 357
             |....|..|.| |:.  ..|....|:.:...|.:|.|.....|:.|  ::.|    ||  :|..
Zfish   361 -HLKRHLSEPSE-DVRNCKQLLSFRSISAPNSSPQREPINLHYKSSPVDNYDFSDSIPE--EPID 421

  Fly   358 VN-----RGLDLDKI 367
            ::     |...|||:
Zfish   422 LSAKTLKRFTALDKV 436

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rhiNP_536794.1 CHROMO 22..72 CDD:237991 21/49 (43%)
ChSh 357..411 CDD:294039 4/16 (25%)
cbx4NP_991312.1 Chromo 13..60 CDD:278797 22/53 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1628171at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.010

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