DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rhi and Cbx7

DIOPT Version :9

Sequence 1:	NP_536794.1	Gene:	rhi / 44879	FlyBaseID:	FBgn0004400	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_006521207.1	Gene:	Cbx7 / 52609	MGIID:	1196439	Length:	251	Species:	Mus musculus

Alignment Length:	239	Identity:	44/239 - (18%)
Similarity:	85/239 - (35%)	Gaps:	68/239 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 YVVEKILGKRFVNGRPQVLVKWSGFPNENNTWEPLENVGNCMKLVSDFESE-------------- 74
            :.||.|..||...|:.:.||||.|:|.:.:||||.|::.: .:||..:|.:
Mouse    11 FAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILD-PRLVMAYEEKEERDRASGYRKRGP 74

  Fly    75 ---------VFRLHRKAAAKSVGKSKSSPSSSGPL---------------ITENGP--------- 106
                     ::.:..:::.|:.|..|...|.:.||               :.|.||
Mouse    75 KPRRLLLQRLYSMDLRSSHKAKGNEKLCFSLARPLRSGSPMGVVKAGVAELVEKGPLVPTLPFPL 139

  Fly   107 -----------SSSKKTQQHSKSVQAKNTAGMSKMNQKKGKNIKKTAGKIKDIENYPKTQM---- 156
                       .|.||.......:::.:......:.:....::.:|.|..:.:|..|:.:.
Mouse   140 RKARKAHKYLRLSRKKFPPRGPHLESHSHRRELSLQESAAPDVVQTPGDWEPMEQAPEEEAEADL 204

  Fly   157 -----PSTSQVSTDSTEVFDGNPSATTTNMIKSPRIQSLFSDLN 195
                 |.|..:.:....|.|...::.|....::...:..|.|.|
Mouse   205 TNGPPPWTPTLPSSEVTVTDITANSVTVTFREAQAAEGFFRDRN 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rhi	NP_536794.1	CHROMO	22..72	CDD:237991	19/47 (40%)
rhi	NP_536794.1	ChSh	357..411	CDD:294039
Cbx7	XP_006521207.1	CD_Cbx7	7..62	CDD:349293	20/51 (39%)
Cbx7	XP_006521207.1	CBX7_C	209..240	CDD:375056	5/30 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920