DRSC/TRiP Functional Genomics Resources

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Protein Alignment rhi and Mphosph8

DIOPT Version :9

Sequence 1:NP_536794.1 Gene:rhi / 44879 FlyBaseID:FBgn0004400 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_001017375.2 Gene:Mphosph8 / 290270 RGDID:1305133 Length:851 Species:Rattus norvegicus


Alignment Length:425 Identity:89/425 - (20%)
Similarity:157/425 - (36%) Gaps:110/425 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 DHVEEYVVEKILGKRFVNGRPQVLVKWSGFPNENNTWEPLENVGNCMKLVSDFESEVFRLHRKAA 83
            |..:.:.||:||..:...|:....|:|.|:.::::||||..::.:|.:::.:|..:|.....||.
  Rat    54 DGEDVFEVERILDMKCEGGKNLYKVRWKGYTSDDDTWEPEVHLEDCKEVLLEFRKKVAENKAKAV 118

  Fly    84 AKSVGK---------SKSSPSSSGPLITENGPSSSKKTQQHSKSVQAKNTAGMSKMNQKKGKNIK 139
            .|.:.|         :.|.....|....:..|...|      |.::.|.......:.:|:.|   
  Rat   119 RKDIQKLSLNNDIFEADSDIDQQGDTKEDTSPRKKK------KKIKYKEDKSPDDLRKKRAK--- 174

  Fly   140 KTAGKIKDIENYPKTQMPSTSQVSTDSTEVFDGNPSATTTNMI----------KSPRIQSLFSDL 194
              .||:||   ..||::.|||::..     ||    ..|...|          |.|:    ..::
  Rat   175 --MGKLKD---KFKTELESTSEILG-----FD----VKTKKRILEVKEELKDSKKPK----KDEI 221

  Fly   195 NLIEPTKDKDVGDTSLK--------TPPKSRRLIEFPQREDAPLSSKHVSPMLIRKESQPLQSSC 251
            ...:.||..|:.|..:|        ...|..|.|:.|...::|..|     ..:..||:...|..
  Rat   222 KETKKTKRADIRDLKIKIREDVKDNRKTKKERYIDSPLESESPNDS-----FTLEDESEDFLSDN 281

  Fly   252 TDDSDLGESSSSMSLPTVSSTSSEKSI-----------KVTK--------SEPKTLGQIKFSS-- 295
            .:..::..:.......||..:..||.:           :|.:        .|||.:.:::.::  
  Rat   282 KEKQNVRTAKDKTGQDTVQESIFEKHLDDLISIEEAGTRVRRKKKQPRKFEEPKEIKKLENTNNF 346

  Fly   296 ----------RSSDGGHA---ASSLGAPKEGDI--GLDLSG------SDSMDSEVESMRRCPRRK 339
                      |:.|.|.:   .|.|.:|.....  .|.|||      |..:..|.:..:..|:.|
  Rat   347 LERKMIPKKQRNQDKGRSNPELSKLPSPVFAQTMKSLRLSGEEKGLKSSDLAEEEKERKNEPKEK 411

  Fly   340 RKKTYPDW-------KFPEMTKPF-GVNRGLDLDK 366
            .:|.| |:       |.|:..|.| .:....||.|
  Rat   412 YQKRY-DFDKEEKARKEPKGLKSFKEIRNAFDLFK 445

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rhiNP_536794.1 CHROMO 22..72 CDD:237991 13/49 (27%)
ChSh 357..411 CDD:294039 3/10 (30%)
Mphosph8NP_001017375.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 21..54 89/425 (21%)
CHROMO 58..109 CDD:214605 14/50 (28%)
Histone H3K9me3 binding. /evidence=ECO:0000250|UniProtKB:Q99549 80..87 2/6 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 133..174 7/46 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 240..302 11/66 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 315..428 22/113 (19%)
ANK 586..710 CDD:238125
ANK 1 591..620
ANK repeat 594..622 CDD:293786
Ank_2 597..686 CDD:289560
ANK repeat 624..655 CDD:293786
ANK 2 624..653
ANK repeat 657..686 CDD:293786
ANK 3 657..686
ANK 4 690..719
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1911
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1628171at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.820

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