DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rhi and cec-5

DIOPT Version :9

Sequence 1:	NP_536794.1	Gene:	rhi / 44879	FlyBaseID:	FBgn0004400	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001370694.1	Gene:	cec-5 / 177537	WormBaseID:	WBGene00017993	Length:	374	Species:	Caenorhabditis elegans

Alignment Length:	341	Identity:	80/341 - (23%)
Similarity:	130/341 - (38%)	Gaps:	94/341 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 NDHVEEYVVEKILGKRF--VNGRPQVLVKWSGFPN---ENNTWEPLENVGNCMKLVSDFESEVFR 77
            :|..|::.||||:..||  ...:|..||.|.|:||   .:..||  ..:.||..|:..::..
Worm   109 DDPDEDFAVEKIIAHRFSGKKNKPLFLVMWRGYPNPVSHSEMWE--NELSNCKDLLEAYKDS--- 168

  Fly    78 LH--RKAAAKSVGKSKSSPSSSGPLITENGPSSSKKTQQHSKSVQAKNTAGMSKMNQKKGKNIKK 140
             |  :....|...|.|.|..|         |..|.|::....|            ::::.:.:|
Worm   169 -HDMKPPPVKKSNKKKGSKKS---------PKKSAKSKDDDSS------------DEEEEEEVK- 210

  Fly   141 TAGKIKDIENYPKTQMPSTSQVSTDSTEVFDGNPSATTTNMIKSPRIQSLFSDLNLIEPTKDKDV 205
                    |..||....||.:.::|..|  :..|.||..:. ||.|.::         |.::.|.
Worm   211 --------EKSPKKSSKSTKRAASDDDE--EEEPVATKKSK-KSKRAET---------PEEEDDE 255

  Fly   206 GDTSLKTPPKSR--RLIEFPQRED--------APLSSK-HVSPMLIRKESQPLQSSCTDDSDLGE 259
            .:..:|||.|::  :..|.|:.||        .|..|| ..||    |:|:..::|..:|.|
Worm   256 EEEVVKTPKKTKKSKRAETPEEEDEVEEEVVKTPKKSKSSKSP----KKSKRAETSDEEDED--- 313

  Fly   260 SSSSMSLPTVSSTSSEKSIKVTKSEPKTLGQIKFSSRSSDGGHAASSLGAPKEGDIGLDLSGSDS 324
                       ....:::.|.:|.:.|.    |.|.|      .|...|..:|.......|||:.
Worm   314 -----------EEDEKEAPKSSKKQEKA----KSSKR------VAEDSGNEEEDQDNTSGSGSEG 357

  Fly   325 MDSEVESMRRCPRRKR 340
            .:.|.|:.....|:.|
Worm   358 EEEEEEASSNGKRKSR 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rhi	NP_536794.1	CHROMO	22..72	CDD:237991	19/54 (35%)
rhi	NP_536794.1	ChSh	357..411	CDD:294039
cec-5	NP_001370694.1	CD_CSD	115..167	CDD:421697	18/53 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910