DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rhi and cec-8

DIOPT Version :9

Sequence 1:	NP_536794.1	Gene:	rhi / 44879	FlyBaseID:	FBgn0004400	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_497198.1	Gene:	cec-8 / 175202	WormBaseID:	WBGene00021913	Length:	679	Species:	Caenorhabditis elegans

Alignment Length:	342	Identity:	84/342 - (24%)
Similarity:	132/342 - (38%)	Gaps:	56/342 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 NDHVEEYVVEKILGKRFVNGR---PQVLVKWSGFPNE-NNT--W-EPLENVGNCMKLVSDFESEV 75
            :|..:|||||||:..|:.|.|   |..||.|.|||:. :||  | |.||   ||.:|:..:..|
Worm   108 DDGSKEYVVEKIVAHRYPNDRLNQPLYLVMWRGFPDPVSNTEMWGEELE---NCQELLDAYNEE- 168

  Fly    76 FRLH---------RKAAAKSVGKSKSSPSSSGPLITENGPSSSKKTQQHSKSVQAKNTAGMSKMN 131
               |         .|...||..:..|..|.......|..|......::.:.||...::...|..:
Worm   169 ---HDIDLSKTVMNKPPKKSKHQDTSDDSEESEDEEEKSPRKRSSKKRRAASVSDSDSDSDSDFD 230

  Fly   132 QKKGKNIKKTAGKIKDIENYPKTQMPSTSQVSTDSTEVFDGNPSATTTNMIKSPRIQSLFSDLNL 196
            :||.|..|....| :|..:...::|....:.|..|.:         :....||.:.:...:|
Worm   231 KKKWKKNKAKRSK-RDDSSDDDSEMERRRKKSKKSKK---------SKKFKKSEKRKRAVND--- 282

  Fly   197 IEPTKDKDVGDTSLKTPPKSRRLI--EFPQREDAPLSSKHVSPMLIRKESQPLQSSCTDDSDLGE 259
             ..:.|:|..:...|...||::.:  ...:.|:...|||..|.. .:|||...|.:...:.::.|
Worm   283 -SSSDDEDEEEKPEKRSKKSKKAVIDSSSEDEEEEKSSKKRSKK-SKKESDEEQQASDSEEEVVE 345

  Fly   260 SSSSMSLPTVSSTSSEKSIKVTKSEPKTLGQIKFSSRSSDGGHAASSLGAPKEGDIGLDLSGSDS 324
                          .:|:.|..|..||... :|..|..|.|......:...|...|....:...|
Worm   346 --------------VKKNSKSPKKTPKKTA-VKEESEESSGDEEEEVVKKKKSSKINKRKAKESS 395

  Fly   325 MDSEVESMRRCPRRKRK 341
            .|.| |.:...|::|.|
Worm   396 SDEE-EEVEESPKKKTK 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rhi	NP_536794.1	CHROMO	22..72	CDD:237991	26/56 (46%)
rhi	NP_536794.1	ChSh	357..411	CDD:294039
cec-8	NP_497198.1	CD_CEC-4_like	114..167	CDD:349317	25/55 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910