DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rhi and cec-3

DIOPT Version :9

Sequence 1:	NP_536794.1	Gene:	rhi / 44879	FlyBaseID:	FBgn0004400	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_495652.1	Gene:	cec-3 / 174265	WormBaseID:	WBGene00011636	Length:	339	Species:	Caenorhabditis elegans

Alignment Length:	311	Identity:	63/311 - (20%)
Similarity:	125/311 - (40%)	Gaps:	68/311 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 EEYVVEKILGKRFVNGRPQVLVKWSGFPNENNTWEPLENVGNC-MKLVSDF--------ESEVFR 77
            |.:.|||||..:..:....:.|:|.|:..:.:||||.|::..| .::|:::        ::|:..
Worm    22 EIFEVEKILAHKVTDNLLVLQVRWLGYGADEDTWEPEEDLQECASEVVAEYYKKLKVTDKTELIE 86

  Fly    78 L-----------HRKAAAKSVGKSKSSPSSSGPLITENGPSSSKKTQQHSKSVQAKNTAGMSKMN 131
            |           ..|..:|:|...:|:..|.|...|......|||:.::...|.:|.....:|..
Worm    87 LLQKQIKKNKSQKSKKRSKTVSDHESNHDSDGSYGTPKTSKKSKKSAKNETPVSSKVPKVPTKAA 151

  Fly   132 QKK----------GKNIKKTAGKIKDIENYPKTQMPSTSQVSTDSTEVFDGNPSATTTNMIKSPR 186
            .|.          ..|.||.|.:::|      |:.....:.|:|       :.:.||..:....:
Worm   152 LKSYEATVSGPVAPNNAKKAAMEVRD------TRRNWLDEESSD-------DEAETTAPLSDVEK 203

  Fly   187 IQSLFSDLNLIEPTKDKDVGDTSLKTPPKSRRLIEFPQREDAPLSS----------KHVS----- 236
            |.|....:..:|...::.|...|  ||||.|.::......::|::|          |.::
Worm   204 IASKVKVVKAVEEKAEEPVKRPS--TPPKPREVVIKKDPSESPVASASSVIPTSKRKSINAETSN 266

  Fly   237 --------PMLIRKESQPLQSSCTDDSDLGESSSSMSLPTVSSTSSEKSIK 279
                    |::::.|:..........:|:..:.:.:.|.|.|:|...|.::
Worm   267 GRQRTLAPPVIVKDETTWTVDGIARHTDVDNTKTKLILMTNSATGERKVVE 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rhi	NP_536794.1	CHROMO	22..72	CDD:237991	16/58 (28%)
rhi	NP_536794.1	ChSh	357..411	CDD:294039
cec-3	NP_495652.1	Chromo	25..75	CDD:278797	15/49 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22812
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.960