DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rhi and CDYL2

DIOPT Version :9

Sequence 1:	NP_536794.1	Gene:	rhi / 44879	FlyBaseID:	FBgn0004400	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_011521168.1	Gene:	CDYL2 / 124359	HGNCID:	23030	Length:	540	Species:	Homo sapiens

Alignment Length:	302	Identity:	72/302 - (23%)
Similarity:	120/302 - (39%)	Gaps:	65/302 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 PPNDHVEEYVVEKILGKR-FVNGRPQVLVKWSGFPNENNTWEPLENVGNCMKLVSDF-------- 71
            |....|||  ||:|:.|| ...|:.:.|::|.|:.:..:||||..::.:|.:.:.:|
Human    35 PLPSRVEE--VERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHMSKD 97

  Fly    72 -------ESEVFRLHRKAAAKSVGKSKSSPSSSG--------------PLITENGPSSSKKT--- 112
                   :|...:|.|.:...||.|....||..|              ||.......|.|.:
Human    98 KRIKSGKQSSTSKLLRDSRGPSVEKLSHRPSDPGKSKGTSHKRKRINPPLAKPKKGYSGKPSSGG 162

  Fly   113 QQHSKSVQAKNT-AGMSKMNQKKGKNIKKT--AGKIKDIENYPK-TQMPS---TSQVSTDSTEVF 170
            .:.:|:|..:.| :|:..|..||.:|..:.  ||..||..::.. :..|.   ...|........
Human   163 DRATKTVSYRTTPSGLQIMPLKKSQNGMENGDAGSEKDERHFGNGSHQPGLDLNDHVGEQDMGEC 227

  Fly   171 DGNPSATTTNMIKSPRIQSLFSDLNLIEPTK-----DKD-VGDTSLKTPPKSR----RLIEFPQR 225
            |.|.:....|.:.|....   ..|||..|.|     :|| |.|..|:...:..    |..:...|
Human   228 DVNHATLAENGLGSALTN---GGLNLHSPVKRKLEAEKDYVFDKRLRYSVRQNESNCRFRDIVVR 289

  Fly   226 EDAP-----LSSK-----HVSPMLIRKESQPLQSSCTDDSDL 257
            ::..     |||:     .::|.::::..:.|.::.||||.|
Human   290 KEEGFTHILLSSQTSDNNALTPEIMKEVRRALCNAATDDSKL 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rhi	NP_536794.1	CHROMO	22..72	CDD:237991	17/65 (26%)
rhi	NP_536794.1	ChSh	357..411	CDD:294039
CDYL2	XP_011521168.1	CHROMO	40..89	CDD:214605	17/50 (34%)
CDYL2	XP_011521168.1	crotonase-like	286..482	CDD:119339	11/46 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810