DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rhi and Cbx1

DIOPT Version :9

Sequence 1:	NP_536794.1	Gene:	rhi / 44879	FlyBaseID:	FBgn0004400	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001349489.1	Gene:	Cbx1 / 12412	MGIID:	105369	Length:	185	Species:	Mus musculus

Alignment Length:	217	Identity:	57/217 - (26%)
Similarity:	90/217 - (41%)	Gaps:	52/217 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 QRPNLGLVDAPPNDHVEEYVVEKILGKRFVNGRPQVLVKWSGFPNENNTWEPLENVGNCMKLVSD 70
            ::.|...|:....:..|||||||:|.:|.|.|:.:.|:||.||.:|:|||||.||: :|..|:::
Mouse     3 KKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENL-DCPDLIAE 66

  Fly    71 FESEVFRLHRKAAAKSVGKSKSSPSSSGPLITENGPSSSKKTQQHSKSVQAKNTAGMSKMNQKKG 135
            |.......|.  ..||.|..:.:.|.|    .:.|..|..|                     ||.
Mouse    67 FLQSQKTAHE--TDKSEGGKRKADSDS----EDKGEESKPK---------------------KKK 104

  Fly   136 KNIKKTAGKIKDIENYPKTQMPSTSQVSTDS------------TEVFDGNPSATTTNMIKSPRIQ 188
            :..:|..|..:.:|       |.....:|||            ::..|..|:....  :|.|::.
Mouse   105 EESEKPRGFARGLE-------PERIIGATDSSGELMFLMKWKNSDEADLVPAKEAN--VKCPQVV 160

  Fly   189 SLFSDLNLI---EPTKDKDVGD 207
            ..|.:..|.   .|::|.|..|
Mouse   161 ISFYEERLTWHSYPSEDDDKKD 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rhi	NP_536794.1	CHROMO	22..72	CDD:237991	26/49 (53%)
rhi	NP_536794.1	ChSh	357..411	CDD:294039
Cbx1	NP_001349489.1	CD_HP1beta_Cbx1	20..69	CDD:349297	26/49 (53%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..124		17/94 (18%)
		CSD_HP1beta_Cbx1	112..169	CDD:349301	11/65 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22812
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920