DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rhi and CBX3

DIOPT Version :9

Sequence 1:	NP_536794.1	Gene:	rhi / 44879	FlyBaseID:	FBgn0004400	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_009207.2	Gene:	CBX3 / 11335	HGNCID:	1553	Length:	183	Species:	Homo sapiens

Alignment Length:	98	Identity:	39/98 - (39%)
Similarity:	56/98 - (57%)	Gaps:	15/98 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 DAPPNDHVEEYVVEKILGKRFVNGRPQVLVKWSGFPNENNTWEPLENVGNCMKLVSDFESEVFRL 78
            :|.|    ||:||||:|.:|.|||:.:..:||.||.:.:|||||.||: :|.:|:     |.|..
Human    24 EAEP----EEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENL-DCPELI-----EAFLN 78

  Fly    79 HRKAAAKSVGKSKSSPSSSGPLITENGPSSSKK 111
            .:||..:..|..:.|.|.|     |:..|.|||
Human    79 SQKAGKEKDGTKRKSLSDS-----ESDDSKSKK 106

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rhi	NP_536794.1	CHROMO	22..72	CDD:237991	24/49 (49%)
rhi	NP_536794.1	ChSh	357..411	CDD:294039
CBX3	NP_009207.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28		2/7 (29%)
		CD_HP1gamma_Cbx3	29..78	CDD:349299	25/54 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	79..125		11/33 (33%)
		CSD_HP1gamma_Cbx3	116..173	CDD:349303
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820