DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rhi and cbx2

DIOPT Version :9

Sequence 1:	NP_536794.1	Gene:	rhi / 44879	FlyBaseID:	FBgn0004400	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_002942815.2	Gene:	cbx2 / 100491304	XenbaseID:	XB-GENE-970247	Length:	477	Species:	Xenopus tropicalis

Alignment Length:	440	Identity:	85/440 - (19%)
Similarity:	147/440 - (33%)	Gaps:	160/440 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 YVVEKILGKRFVNGRPQVLVKWSGFPNENNTWEPLENVGNCMKLVS----DFESEVFRLHR---- 80
            :..|.||.||...|..:.||||.|:.:::|:|||.||:.:...|::    :.|.|:....|
Frog    12 FAAECILSKRLRKGTAEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKREQEKELRNKKRGKRP 76

  Fly    81 --------------KAAAKSVGKSKSSPSSSGPLITENGPSSSKKTQQ----------------- 114
                          ||.:.|...|.||.|||....:.:...|...|||
Frog    77 RGRPRKNVETDIPLKAKSSSSSSSSSSSSSSSSSSSSSSDDSDADTQQRNPRPRDSHPVPQKKAP 141

  Fly   115 -----------------------------------------------------------HSKSVQ 120
                                                                       |||.:|
Frog   142 AVLARPELKEPVRKKRGRKPLPPEQKLPRRAKGAKPGPKGSLNKLQPGHSVQGFQALKTHSKDMQ 206

  Fly   121 AKNTAGMSKMNQKKGKNIKKTAGKIKDIENYPKTQMPST-----------SQVSTDSTE------ 168
            :      |..|:..|.:.:..:...|:..:.|....|.:           ::::.:|::
Frog   207 S------SSNNRPGGLSAELLSSIAKNSPSQPNGSSPRSLSWQSSIVHYMNRINQNSSQPGRKPA 265

  Fly   169 --VFDGNPSATTTNMIKSPR----IQSLFSDLNLIEPTKDKDVGDTSLKTPPKSRRLIEFPQRED 227
              .|:...|...:..:..||    |.......:.:..::::....|...|||.:....|.|
Frog   266 GSTFNAKRSCLDSKSLFKPRGEVEISPAMPKTSKVHESEEQTHSHTVQSTPPVAAGSNENP---- 326

  Fly   228 APLSSKHVSPMLIRKESQPLQSSCTDDSDLGESSSSMSLPTVSSTSSEKSIKVTKSE----PKTL 288
                 .|.:|  ::.::|.:::.....:......|:.| |:|...:|.|:.|::|..    |..|
Frog   327 -----SHTAP--VQTKTQGMRAVAASPAGQNTQKSNGS-PSVGVATSCKADKISKKTGVVGPARL 383

  Fly   289 G----QIKFSSRSSDGGHAASSLGAPKEGDIGL-DLSGSD--SMDSEVES 331
            |    |:          |.|:....|.||...| |||..|  |:||:.:|
Frog   384 GTTEPQV----------HPATERAQPTEGQRELADLSTGDDSSLDSDHDS 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rhi	NP_536794.1	CHROMO	22..72	CDD:237991	18/51 (35%)
rhi	NP_536794.1	ChSh	357..411	CDD:294039
cbx2	XP_002942815.2	CD_Cbx2	9..61	CDD:349294	18/48 (38%)
cbx2	XP_002942815.2	CBX7_C	436..468	CDD:407338
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920