Protein Alignment sub and kif5ab

DIOPT Version :10

• Sequence 1: NP_611260.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: XP_009301044.1
• Gene: kif5ab / 799274
• ZFINID: ZDB-GENE-110510-3
• Length: 1050
• Species: Danio rerio
• Alignment Length: 601
• Identity: 154/601 - (25%)
• Similarity: 240/601 - (39%)
• Gaps: 171/601 - (28%)

  Fly    79 ADSSNVETGPQVFLRLRPVKDASKAYIVSE--EANVLITSCKVDSTSNNVNRMEKHFGFTSIFDS 141
            ||.| .|...:|..|.||:..       ||  ..:..:.:.:.|.|   |....:.:.|..:|.:
Zfish     2 ADIS-AECNIRVLCRFRPLNQ-------SEILRGDKFMPTFQGDDT---VIIAGRSYVFDKVFPT 55

  Fly   142 TVGQRDIYDTC---VGPKIMEEECVTIMTYGTSGSGKTYTLLG---DDVRAGIIPRALENIFT-I 199
            ...|..:|:||   :...:::....||..||.:.||||||:.|   |....|||||..|:||. |
Zfish    56 NCTQEQVYNTCAQQIVKDVLDGYNGTIFAYGQTSSGKTYTMEGKLHDANGRGIIPRIAEDIFNHI 120

  Fly   200 YQDTVFRSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVIDGDHMFETKAS 264
            |                                                   .:|.:..|..|
Zfish   121 Y---------------------------------------------------TMDENLEFHIK-- 132

  Fly   265 TDVSVLVWVSFVEIYNELVYDLLAIPPKQDKLGEVPRKNLKIVGNKGHV-FIKGLTSVFVTSSEE 328
                    ||:.|||.:.:.|||          :|.:.||.:..:|..| ::||.|..||:|.||
Zfish   133 --------VSYFEIYMDKIRDLL----------DVTKTNLSVHEDKNRVPYVKGCTERFVSSPEE 179

  Fly   329 ALRLLRLGQQRSTYASTSVNANSSRSHCVFTVDILKYNRSGITTQSSYKFC------DLAGSERV 387
            .:.|:..|:.....|.|::|.:|||||.:|.::|.:.:     .::..|.|      ||||||:|
Zfish   180 VMDLIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQEH-----VETEQKLCGKLYLVDLAGSEKV 239

  Fly   388 NNTGTSGLRLKEAKNINTSLMVLGRCLDAASTVQKKKNADIIPYRDSKLTMLLQAALLGKEKLAM 452
            :.||..|..|.||||||.||..||..:.|.:...|..    :||||||:|.:||.:|.|..:..|
Zfish   240 SKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTH----VPYRDSKMTRILQDSLGGNCRTTM 300

  Fly   453 IVTVTPLDKYYEENLNVLNFASIAKNI-----IFKEPVIKQHRVSYCGFMEFSKMSTCEGGDYTK 512
            .:..:|......|..:.|.|...||.|     :..|...:|.:..|    |..|       :..|
Zfish   301 FICCSPSAYNDAETKSTLMFGQRAKTIMNSASVNLELTAEQWKRKY----EKEK-------EKNK 354

  Fly   513 ELEDENVRLQLEIEQLKYDHVL-------------------------QMQLLEEKLRRELTATYQ 552
            :|::...||:.|:...:....:                         |.:|:.|    :..:.|:
Zfish   355 DLKESMQRLEAELNHWRNGESVVLITPVSPAECDVTEDTAVDNQSHGQTELIPE----QHNSRYE 415

  Fly   553 EIIQNNKKQYED-------ECE--KKLLIAQRESEFMLSSQR----------RRYEEQIEDLKDE 598
            |.||...:|.:|       :|:  :||.....:.|.:|:..|          ||.:...|..|.|
Zfish   416 EEIQQLYRQLDDKDDEINLQCQLVEKLKEQMLDQEELLACARADLERVQCDVRRLQADSESSKLE 480

  Fly   599 IEELKNPASDTDISDD 614
            ::|:.....:..:|.|
Zfish   481 VQEVLQALEELALSYD 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sub	NP_611260.1	KISc	89..477	CDD:276812	114/403 (28%)
		GBP_C	<512..603	CDD:293879	26/134 (19%)
		coiled coil	576..586	CDD:293879	3/19 (16%)
		coiled coil	592..603	CDD:293879	4/10 (40%)
kif5ab	XP_009301044.1	KISc_KHC_KIF5	7..327	CDD:276820	117/409 (29%)
		SMC_prok_B	<408..738	CDD:274008	21/93 (23%)
		EnvC	700..>921	CDD:443969
		Khc_CBD_cc	853..922	CDD:467880