Protein Alignment sub and Kif23

DIOPT Version :9

• Sequence 1: NP_001286548.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: XP_006511515.1
• Gene: Kif23 / 71819
• MGIID: 1919069
• Length: 967
• Species: Mus musculus
• Alignment Length: 623
• Identity: 170/623 - (27%)
• Similarity: 282/623 - (45%)
• Gaps: 114/623 - (18%)

  Fly    82 SNVETGPQVFLRLRPVK--DASKAYIVSEEANVLITSCKVDSTSNNVNRMEKHFGFTSIFDSTVG 144
            :|::....|:.|:||:.  |......|.....:.:.:.:....:.|.:..|..:.|..:|.:...
Mouse    20 TNLKDPVGVYCRVRPLSFPDQECCVEVINSTTLQLHTPEGYRLNRNGDYKETQYSFKRVFGTHTT 84

  Fly   145 QRDIYDTCVGPKIMEEECV-----TIMTYGTSGSGKTYTLLGDDVRAGIIPRALENIFTIYQDTV 204
            |::::|....|.:  ::.:     .:.|||.:|||||||:.|.....|::||.|..||.....
Mouse    85 QKELFDVVANPLV--DDLIHGKNGLLFTYGVTGSGKTYTMTGSPGSGGLLPRCLNMIFNSIGS-- 145

  Fly   205 FRSPKLKLINGSIVFLQDDASLKELQI---------RKKLLDLCPDISAHHQRLKQVIDGDHMFE 260
            |::.:       .||..:|.:..|:|.         :::.|.:....|:..|...:..|..::.|
Mouse   146 FQAKR-------YVFKSNDRNSMEIQCEVDALLERQKREALPIPKTPSSKRQADPEFADMINVQE 203

  Fly   261 TKASTDV---SVL-VWVSFVEIYNELVYDLL------AIPPKQDKLGEVPRKNLKIV-------- 307
            ...:.:|   ||. |:||::||||..:||||      .|.||.:.. ..|.:|.:.|
Mouse   204 FCKAEEVDEDSVYGVFVSYIEIYNNYIYDLLEEVQFDPIKPKWNGC-STPMRNAESVLPQSKTLR 267

  Fly   308 GNKGH-VFIKGLTSVFVTSSEEALRLLRLGQQRSTYASTSVNANSSRSHCVFTVDILK------- 364
            .:|.| :::.|.|.|.|.|:|||..:...||::...|:|.:|..|||||.||::.:::
Mouse   268 EDKNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFSIKLVQAPLDADG 332

  Fly   365 ----YNRSGITTQSSYKFCDLAGSERVNNTGTSGLRLKEAKNINTSLMVLGRCLDAASTVQKKKN 425
                ..:..||. |.....|||||||.|.|...|.||:||.|||.|||.|..|::.....|....
Mouse   333 DNVLQEKEQITI-SQLSLVDLAGSERTNRTKAEGNRLREAGNINQSLMTLRTCMEVLRENQTYGT 396

  Fly   426 ADIIPYRDSKLTMLLQAALLGKEKLAMIVTVTPLDKYYEENLNVLNFASIAKNIIFKEPVIKQHR 490
            ..::||||||||.|.:....|:.|:.|||.|.|..:.|||:|.|:.||.:.:.:....||.|
Mouse   397 NKMVPYRDSKLTHLFKNYFDGEGKVRMIVCVNPKAEDYEESLQVMRFAEVTQEVEVARPVDK--- 458

  Fly   491 VSYCG--------------------------FMEFSKMSTCEGGDYTKELEDENVRLQLEIEQLK 529
             ..||                          ...|..:..|:    ..::.||....:| .:.|:
Mouse   459 -VICGLTPGRRYRNLPRGGPVGDEPLVPEVILQSFPPLPPCK----LLDINDEETLPKL-ADTLE 517

  Fly   530 YDHVLQMQLLEEKLRRELTATYQEIIQ------NNKKQYEDECEKKLLIAQRESEFMLSSQR--- 585
            ..|.|: ||:.|.|.::..| ::.:::      :||:.|..|   ||    .|.|.::|.|:
Mouse   518 KRHHLR-QLMTEDLNKKCLA-FKALLKEFDNSLSNKENYVQE---KL----NEREKVISGQKLEI 573

  Fly   586 RRYEEQIEDLKDEIEELKNPASDTDISDDPNESKSPIE 623
            .|.|::.:.|:.:||.|:.  :.|...:|....:..:|
Mouse   574 ERLEKKNKTLEYKIEILEK--TTTIYEEDKRNLQQELE 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sub	NP_001286548.1	KISc	89..477	CDD:276812	132/433 (30%)
		Kinesin	93..479	CDD:278646	131/431 (30%)
		GBP_C	<512..603	CDD:303769	26/99 (26%)
		coiled coil	576..586	CDD:293879	4/12 (33%)
		coiled coil	592..603	CDD:293879	3/10 (30%)
Kif23	XP_006511515.1	KISc_KIF23_like	24..448	CDD:276819	132/436 (30%)
		SCP-1	<504..690	CDD:114219	30/118 (25%)
		MKLP1_Arf_bdg	811..913	CDD:374613

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0247
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R641
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840