Protein Alignment sub and Klp68D

DIOPT Version :10

• Sequence 1: NP_611260.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Alignment Length: 543
• Identity: 138/543 - (25%)
• Similarity: 222/543 - (40%)
• Gaps: 138/543 - (25%)

  Fly    89 QVFLRLRPVKDASKAYIVSEEANVLITS--CKVDSTSNNVNRMEKHFGFTSIFDSTVGQRDIYDT 151
            ||.:|.||:.:..::....|..||....  .::.:..:......|.|.:.:.:|::..|..:|..
  Fly    21 QVVVRCRPMSNRERSERSPEVVNVYPNRGVVELQNVVDGNKEQRKVFTYDAAYDASATQTTLYHE 85

  Fly   152 CVGP---KIMEEECVTIMTYGTSGSGKTYTL---LGDDVRAGIIPRALENIFTIYQDTVFRSPKL 210
            .|.|   .::|.....|..||.:|:|||:|:   .|:|...|||||..|.|:.
  Fly    86 VVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRGNDELMGIIPRTFEQIWL------------ 138

  Fly   211 KLINGSIVFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVIDGDHMFETKASTDVSVLVWVSF 275
                                                          |:..|:   :...||.||:
  Fly   139 ----------------------------------------------HINRTE---NFQFLVDVSY 154

  Fly   276 VEIYNELVYDLLAIPPKQDKLGEVPRKNLKIVGNKGHVFIKGLTSVFVTSSEEALRLLRLGQQRS 340
            :|||.|.:.|||  .|..        |:|::......|::..|.::...|.|:.::::::|.:..
  Fly   155 LEIYMEELRDLL--KPNS--------KHLEVRERGSGVYVPNLHAINCKSVEDMIKVMQVGNKNR 209

  Fly   341 TYASTSVNANSSRSHCVFTVDILKYNRSGITTQ-SSYKFCDLAGSERVNNTGTSGLRLKEAKNIN 404
            |...|::|.:|||||.:|.:.|...:....|.: ......|||||||.:.||.|..|||||..||
  Fly   210 TVGFTNMNEHSSRSHAIFMIKIEMCDTETNTIKVGKLNLIDLAGSERQSKTGASAERLKEASKIN 274

  Fly   405 TSLMVLGRCLDAASTVQKKKNADIIPYRDSKLTMLLQAALLGKEKLAMIVTVTPLDKYYEENLNV 469
            .:|..||..:.|.:     :::..:||||||||.|||.:|.|..|..||..:.|.:..|.|.|..
  Fly   275 LALSSLGNVISALA-----ESSPHVPYRDSKLTRLLQDSLGGNSKTIMIANIGPSNYNYNETLTT 334

  Fly   470 LNFASIAKNIIFKEPVIKQHRVSYCGFMEFSKMSTCEGGDYTKELEDENVRL---QLEIEQLKYD 531
            |.:||.||: |..:|:                          |..:.::.:|   |.|||:||..
  Fly   335 LRYASRAKS-IQNQPI--------------------------KNEDPQDAKLKEYQEEIERLKRL 372

  Fly   532 HVLQMQLLEEKLRRELTATYQEIIQNNKKQYEDECEKKLLIAQRESEFMLSSQRRRYEEQIEDLK 596
            ...|.|...||   ::||..|.:.:..|:....|....|                    |:..::
  Fly   373 IGPQQQQRSEK---QVTAKKQRVKKPKKETVTKEMSDSL--------------------QVSTIE 414

  Fly   597 DEIEELKNPASDTDISDDPNESK 619
            ..:|:..:|......||..||::
  Fly   415 QPVEDDSDPEGAESESDKENEAE 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sub	NP_611260.1	KISc	89..477	CDD:276812	109/396 (28%)
		GBP_C	<512..603	CDD:293879	20/93 (22%)
		coiled coil	576..586	CDD:293879	0/9 (0%)
		coiled coil	592..603	CDD:293879	1/10 (10%)
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	113/432 (26%)
		Smc	<431..>580	CDD:440809	3/7 (43%)