Protein Alignment sub and Khc

DIOPT Version :9

• Sequence 1: NP_001286548.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Alignment Length: 642
• Identity: 150/642 - (23%)
• Similarity: 258/642 - (40%)
• Gaps: 195/642 - (30%)

  Fly    77 SAADSSNVETGPQVFLRLRPVKD----ASKAYIVSEEANVLITSCKVDSTSNNVNRMEKHFGFTS 137
            ||......|...:|..|.||:.|    |...::|....||         ..|.::...|.:.|..
  Fly     2 SAEREIPAEDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNV---------EENCISIAGKVYLFDK 57

  Fly   138 IFDSTVGQRDIYDTC---VGPKIMEEECVTIMTYGTSGSGKTYTL---LGDDVRAGIIPRALENI 196
            :|.....|..:|:..   :...::.....||..||.:.||||:|:   :||.|:.|||||.:.:|
  Fly    58 VFKPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDI 122

  Fly   197 FTIYQDTVFRSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVIDGDHMFET 261
            |                                                          :|::..
  Fly   123 F----------------------------------------------------------NHIYAM 129

  Fly   262 KASTDVSVLVWVSFVEIYNELVYDLLAIPPKQDKLGEVPRKNLKIVGNKGHV-FIKGLTSVFVTS 325
            :.:.:..:.  ||:.|||.:.:.|||          :|.:.||.:..:|..| ::||.|..||:|
  Fly   130 EVNLEFHIK--VSYYEIYMDKIRDLL----------DVSKVNLSVHEDKNRVPYVKGATERFVSS 182

  Fly   326 SEEALRLLRLGQQRSTYASTSVNANSSRSHCVFTVDILKYNRSGITTQSSYKF-CDLAGSERVNN 389
            .|:...::..|:.....|.|::|.:|||||.||.:::.:.|.......|...: .||||||:|:.
  Fly   183 PEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLINVKQENLENQKKLSGKLYLVDLAGSEKVSK 247

  Fly   390 TGTSGLRLKEAKNINTSLMVLGRCLDAASTVQKKKNADIIPYRDSKLTMLLQAALLGKEKLAMIV 454
            ||..|..|.||||||.||..||..:.|.:...|..    |||||||||.:||.:|.|..:..:::
  Fly   248 TGAEGTVLDEAKNINKSLSALGNVISALADGNKTH----IPYRDSKLTRILQESLGGNARTTIVI 308

  Fly   455 TVTPLDKYYEENLNVLNF---ASIAKNII-FKEPVIKQHRVSYCGFMEFSKMSTCEGGDYTKELE 515
            ..:|......|..:.|:|   |...||:: ..|.:..:         |:.:.       |.|| :
  Fly   309 CCSPASFNESETKSTLDFGRRAKTVKNVVCVNEELTAE---------EWKRR-------YEKE-K 356

  Fly   516 DENVRLQLEIEQL-------------KYDHVLQMQLLEE-------------------------- 541
            ::|.||:.::|:|             |.:..:.|:.|.|
  Fly   357 EKNARLKGKVEKLEIELARWRAGETVKAEEQINMEDLMEASTPNLEVEAAQTAAAEAALAAQRTA 421

  Fly   542 --------------KLRRELTATYQEIIQ-----NNKKQYEDECEKKLLIAQRESEFMLSSQRRR 587
                          :|..|....||::..     |.:.||.::.:::::    |.|.::::.||.
  Fly   422 LANMSASVAVNEQARLATECERLYQQLDDKDEEINQQSQYAEQLKEQVM----EQEELIANARRE 482

  Fly   588 YE----------EQIEDLKDEIEELKNPASDTDISDD------PNESKSPIEILDDD 628
            ||          ::.|..|:|::|:.....:..::.|      .|::|. |:.|:::
  Fly   483 YETLQSEMARIQQENESAKEEVKEVLQALEELAVNYDQKSQEIDNKNKD-IDALNEE 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sub	NP_001286548.1	KISc	89..477	CDD:276812	109/402 (27%)
		Kinesin	93..479	CDD:278646	109/400 (27%)
		GBP_C	<512..603	CDD:303769	28/158 (18%)
		coiled coil	576..586	CDD:293879	2/9 (22%)
		coiled coil	592..603	CDD:293879	4/10 (40%)
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	110/405 (27%)
		KISc	12..340	CDD:214526	111/410 (27%)
		Apolipoprotein	595..744	CDD:279749

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437853
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940