Protein Alignment sub and Kif12

DIOPT Version :10

• Sequence 1: NP_611260.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: XP_006238315.1
• Gene: Kif12 / 313254
• RGDID: 1308487
• Length: 648
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 146/547 - (26%)
• Similarity: 230/547 - (42%)
• Gaps: 144/547 - (26%)

  Fly    83 NVETGP-------QVFLRLRPVKDASKAYIVSEEANVLITSCKVDSTSNNVNRMEKHFGFTSIFD 140
            |:|.||       ||.||:||:.......  .|::.:..:..:....|......:..|.|.::.|
  Rat    14 NLEQGPEGSETPIQVVLRVRPMSTVELRR--GEQSALHCSGTRTLQVSPPGGGPDVAFRFGAVLD 76

  Fly   141 STVGQRDIYDTCVGPKIMEE------ECVTIMTYGTSGSGKTYTLLGDDVRA-GI-IPRALENIF 197
            ....|.|::..| |.|.:.|      .| |:.|:|.:||||||||.|...:| |: :|.:|..|
  Rat    77 GARTQEDVFRAC-GVKRLGELALRGFSC-TVFTFGQTGSGKTYTLTGPPPQAEGVPVPPSLAGI- 138

  Fly   198 TIYQDTVFRSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVIDGDHMFETK 262
                           :..:..:|.|                         |::.:
  Rat   139 ---------------MQRTFTWLLD-------------------------RMQHL---------- 153

  Fly   263 ASTDVSVLVWVSFVEIYNELVYDLLAIPPKQDKLGEVPRKNLKIVGNKGHVFIKGLTSVFVTSSE 327
               |..|.:..|::|||||.|.|||:    |.....:|.:..|..|    .:::.|..|...|.|
  Rat   154 ---DSPVTLRASYLEIYNEQVQDLLS----QGSPRPLPVRWSKARG----FYVEQLRLVECGSLE 207

  Fly   328 EALRLLRLGQQRSTYASTSVNANSSRSHCVFTVDILKYNRSGITTQS-----------SYKFC-- 379
            ..:.||::|..|...:|.::|..|||||.:.|:.|     |..|:|.           ..|.|
  Rat   208 ALMELLQMGLSRRRSSSHTLNQASSRSHALLTLHI-----SRPTSQQVPPVDLGEPPVGGKLCFV 267

  Fly   380 DLAGSERVNNTGTSGLRLKEAKNINTSLMVLGRCLDAASTVQKKKNADIIPYRDSKLTMLLQAAL 444
            ||||||:|..||:.|..:.||.:||.||:.||.|:......|:|::.  ||:||||||.||..:|
  Rat   268 DLAGSEKVAATGSRGQLMLEANSINRSLLALGHCISLLLDPQRKQSH--IPFRDSKLTKLLADSL 330

  Fly   445 LGKEKLAMIVTVTPLDKYYEENLNVLNFASIAKNIIF-----KEPVIKQHRVSYCGFMEFSKMST 504
            .|:....|:..|:|..:...|.|:.|.:||.|:.|..     |.|.:|..:......:
  Rat   331 GGRGVTLMVACVSPSAQCLPETLSTLRYASRAQRITTRPQGPKSPAVKPPQQVEAELL------- 388

  Fly   505 CEGGDYTKELEDENVRLQLEIEQL------------------KYDHVLQMQLLEEKLRREL---- 547
                    :|::||..|:|:::|:                  .|..:.:..|..||||:|:
  Rat   389 --------QLQEENRCLRLQLDQMYTKAPRVHGARVAWAQRNLYGMLQEFMLENEKLRKEMRQLR 445

  Fly   548 -TATYQEIIQNNKKQYEDECEKKLLIA 573
             :....:..|:...|...|.|::||:|
  Rat   446 SSRDLAQAEQHVLAQQIHELERRLLLA 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sub	NP_611260.1	KISc	89..477	CDD:276812	117/408 (29%)
		GBP_C	<512..603	CDD:293879	20/85 (24%)
		coiled coil	576..586	CDD:293879
		coiled coil	592..603	CDD:293879
Kif12	XP_006238315.1	KISc	25..363	CDD:276812	117/410 (29%)