Protein Alignment sub and Kif3C

DIOPT Version :10

• Sequence 1: NP_611260.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: XP_319556.6
• Gene: Kif3C / 1279749
• VectorBaseID: AGAMI1_002288
• Length: 750
• Species: Anopheles gambiae
• Alignment Length: 618
• Identity: 162/618 - (26%)
• Similarity: 253/618 - (40%)
• Gaps: 167/618 - (27%)

  Fly    89 QVFLRLRPV---KDASKAYIVSEEANVLITSCKVDSTSNNVNRMEKHFGFTSIFDSTVGQRDIY- 149
            :|.:|.||:   :..|....|.:..|.|:   .:|: .|:.|..:|.|.|.:.:.......:||
Mosquito     7 KVVVRCRPMNKREQQSNCKSVIQIDNSLV---NLDN-PNDPNASQKSFQFDNAYGYAATTENIYS 67

  Fly   150 DTCVG--PKIMEEECVTIMTYGTSGSGKTYTLLG--------DDVRA---GIIPRALENIFTIYQ 201
            |.|..  ..::|....||..||.:|.||::|:.|        |...|   |||||:.|
Mosquito    68 DICYSLVESVLEGYNATIFAYGQTGCGKSHTMQGTTYNLSAADPNNANNIGIIPRSFE------- 125

  Fly   202 DTVFRSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVIDGDHMFET-KAST 265
                                                                   |:||. ..::
Mosquito   126 -------------------------------------------------------HIFEAISLAS 135

  Fly   266 DVSVLVWVSFVEIYNELVYDLLAIPPKQDKLGEVPRKNLKIVGNKGHVFIKGLTSVFVTSSEEAL 330
            :|..||.||::|||||.:.|||   ..|..........:|.|..:| |.::.|:...|...::.:
Mosquito   136 EVRYLVLVSYLEIYNETIRDLL---QPQSPAATASTLQIKEVPGEG-VMVQNLSLHTVHGMKQCI 196

  Fly   331 RLLRLGQQRSTYASTSVNANSSRSHCVFTVDILKYNR-----SGIT-TQSSYKFCDLAGSERVNN 389
            .||..|.:.....:|.:|..|||||.:|::.:.:.:.     ||:. .:......|||||||.:.
Mosquito   197 ELLEAGAKNRMVGATLMNIESSRSHSIFSISLEQMSTSVEGDSGVAIKRGKLNLVDLAGSERQSK 261

  Fly   390 TGTSGLRLKEAKNINTSLMVLGRCLDAASTVQKKKNADIIPYRDSKLTMLLQAALLGKEKLAMIV 454
            ||.:|.|||||..||.||..||..:.|....:.:.    |||||||||.|||.:|.|..|..||.
Mosquito   262 TGATGDRLKEATKINLSLSALGNVISALVDGKTRH----IPYRDSKLTRLLQDSLGGNTKTLMIA 322

  Fly   455 TVTPLDKYYEENLNVLNFASIAKNIIF--------KEPVIKQHRVSYCGFMEFSKMSTCEG---- 507
            .::|.|..|:|.|:.|.:||.||||..        |:.::::::..   .|...::...||
Mosquito   323 CISPADYNYDETLSTLRYASRAKNIANKPRVNEDPKDTMLREYQQE---IMRLKELLKGEGSTPP 384

  Fly   508 ----GDY-----------------------TKELEDENV---RLQLEIEQLKYDHVLQMQLL--- 539
                |.|                       .:|.|.:.:   .|..:||::|..:..|||||
Mosquito   385 AAVNGHYDANGLDAEKQALRSQYDQEVTHLRREYEQQRIAKQELVKDIEKIKAYYEQQMQLLTSS 449

  Fly   540 ------EEKLRRELTATYQEIIQNNKKQYED---ECEKKLLIAQRESEFMLSSQRRR----YEEQ 591
                  .||||:...|.  .:...::|:..|   :.:..|:..:|.::..|..:|.|    .|::
Mosquito   450 RQQAADAEKLRQNTPAV--ALAGRDRKEIYDRIKQIKDALIGGERANDIQLKEKRYRNKLASEKR 512

  Fly   592 IEDLKDEIEELKNPASDTDI-----SDDPNESK 619
            |..|...:..::..| |.|:     ||...|.|
Mosquito   513 INALAQALGRIEQSA-DRDLLQGHYSDIQQELK 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sub	NP_611260.1	KISc	89..477	CDD:276812	119/411 (29%)
		GBP_C	<512..603	CDD:293879	26/109 (24%)
		coiled coil	576..586	CDD:293879	1/9 (11%)
		coiled coil	592..603	CDD:293879	2/10 (20%)
Kif3C	XP_319556.6	None