Protein Alignment eif4b and eIF4B

DIOPT Version :9

• Sequence 1: XP_012812217.1
• Gene: eif4b / 448618
• XenbaseID: XB-GENE-988676
• Length: 614
• Species: Xenopus tropicalis
• Sequence 2: NP_001015319.1
• Gene: eIF4B / 3355041
• FlyBaseID: FBgn0020660
• Length: 459
• Species: Drosophila melanogaster
• Alignment Length: 636
• Identity: 159/636 - (25%)
• Similarity: 258/636 - (40%)
• Gaps: 206/636 - (32%)

 Frog     1 MAASAKK-KNKKGKTLTLTDFLADDGGSGGGGGGGGSGGGGGGGGSTYAPKPVNWADETDDLEGD 64
            ||::.|| |..||..::|..||.:....               .|:|...|.:.      :|:||
  Fly     1 MASAGKKGKKNKGTVISLQSFLCNSDAP---------------VGTTQVSKKIR------NLDGD 44

 Frog    65 VSTTWHSNDDDAYRAPPIDRSILPTAPRAAREPNVDRSRLPKSPPFTAFLGNLPYDVTEESIQKF 129
                  .:||.:...|.:.:  |||||||.|  ..|.:.:|...||.|::.|||:|..|:.:.:|
  Fly    45 ------DSDDGSGTLPLVYQ--LPTAPRANR--IFDDNSIPHKAPFIAYINNLPFDANEDDLYEF 99

 Frog   130 FRGLNISAVRLPREPSNPERLKGFGYAEFDDLDSLLRALSLNEESLGNRRIRVDIADQAQDKDRD 194
            |.|:|:.::|||||.....|.:||||.|.::.:.|:..|||.:.|:..||||::::::...:.|.
  Fly   100 FEGINLISLRLPREDGENGRSRGFGYVELENREDLIHVLSLPDPSIKGRRIRIELSNENDQQSRQ 164

 Frog   195 ERS-----FGRDRDRNRESDKTDSSDWRARPSTDSFDDYPPRRGDDSQGDRYRSDRYESDRYRDG 254
            :.:     ||.:.| ||     ||.:|              ||...:.|..:   .|.|:
  Fly   165 KSNRRFDGFGNNGD-NR-----DSGNW--------------RRDSQNNGSNF---GYSSN----- 201

 Frog   255 PRRDGDRYERDRGRDRYDDRNRSDYDRGYDSRGGRRAFG---SGYRRDDDYRGGGGGGDRYGDRY 316
                   :||...|:|....:|.|.:.....|...|...   |..||:         .::..::|
  Fly   202 -------FERSFNRERKSLPDRDDVNTPGSWRTSARPQSIDTSPTRRE---------VEQVSEKY 250

 Frog   317 EERREDRSDRWNGYSRNEERREERAGPTQRPKLNLKPRTAP------------------KDEEGG 363
            .|.|...:||   |||.|..:.|.    :||||||||||.|                  .|::||
  Fly   251 REGRVKIADR---YSREETSKVEE----ERPKLNLKPRTLPLPDVKTIEFEKCDVDEFNLDKQGG 308

 Frog   364 PSAATSRAASIFGGAKPVDTAAREREVEER--LQKEQEKMQQRQLEDDRPRQIERKPRERHPSWR 426
            .|     :.::||.||||||||||.|:|:|  |.::|:|.::.|..:::..:::
  Fly   309 TS-----SLNVFGSAKPVDTAARELEIEQRLALARKQDKGRREQGLNEKLAELQ----------- 357

 Frog   427 SDENQERSRTGSESSQTATGGSSSRISRRRESEKSVENEVFGKDEDAPSPSSKSPKSDSQLPLKV 491
            .|:|...|.:.:.|.:|                    |:.: |:.|                 |:
  Fly   358 VDKNDNESLSATVSWRT--------------------NQDY-KESD-----------------KI 384

 Frog   492 MPAPPPKENAWVKRSTAAPSSRSHSSEYSQSGEMHPDERRQPGTSHPRVDENKVDALEHLAKSGG 556
            ...|..|:                     :..|:|       ..:|.|...|:.:.|.....:.|
  Fly   385 NKCPGEKQ---------------------RDEEIH-------RLNHARGQFNRPELLREKPNANG 421

 Frog   557 HGVGDRNRAPDKKEKRDLDSQGMPESKKMDEQAVKFSHASKYAALSMDGEE 607
                        :.|||..:. ...|||..:..:....::||:.|..:|.|
  Fly   422 ------------ESKRDCRND-RSVSKKTSQNDLVLQSSNKYSGLDNEGSE 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eif4b	XP_012812217.1	RRM_eIF4B	109..185	CDD:240848	32/75 (43%)
eIF4B	NP_001015319.1	RRM	<72..268	CDD:223796	67/242 (28%)
		RRM_eIF4B	79..155	CDD:240848	32/75 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I9511
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	149	1.000	Inparanoid score	I4281
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1530583at2759
OrthoFinder	1	1.000	-	-		FOG0007285
OrthoInspector	1	1.000	-	-		oto105251
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1292
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.090