Protein Alignment sdt and magu-1

DIOPT Version :10

• Sequence 1: NP_001033835.2
• Gene: sdt / 44861
• FlyBaseID: FBgn0261873
• Length: 2020
• Species: Drosophila melanogaster
• Sequence 2: NP_497201.1
• Gene: magu-1 / 190302
• WormBaseID: WBGene00021914
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 542
• Identity: 149/542 - (27%)
• Similarity: 234/542 - (43%)
• Gaps: 126/542 - (23%)

  Fly  1518 AMPLPRGESPPPVPMPPLATMPMSMPVNLPMSACFGTLNDQNDN--IRIIQIEKSTEPLGATVRN 1580
            |..:..|...|.:|..|...                   |::|.  ::|::|.:..||||||::.
 Worm   101 AQEISAGRFAPQLPDVPFEV-------------------DEDDGVAVKIVRIVRRGEPLGATIKC 146

  Fly  1581 EGEAVVIGRIVRGGAAEKSGLLHEGDEILEVNGQELRGKTVNEVCALLGAM-QGTLTFLIVPAGS 1644
            |...|.:.||:..|.|::||.:.|||.:|||||..:..|...|:..||... .|.:||.::||
 Worm   147 ERGKVYVARIMANGVADRSGCIQEGDRVLEVNGITVADKEPREIVKLLDKCDNGIITFKLIPA-- 209

  Fly  1645 PPSVGVMGGTTGSQLAGLGGAHRDTAVLHVRAHFDYDPEDDLYIPCRELGISFQKGDVLHVISRE 1709
                     ....:|.....:||     :.||.|||||..|...||.|..|||:.||:|.::..:
 Worm   210 ---------EINQKLKQKKSSHR-----YARALFDYDPWQDKRHPCPEAAISFRGGDILEILDEK 260

  Fly  1710 DPNWWQAYR---------------EGEEDQTLAGLIPSQSFQHQRETMKLAIAEEAGLARSRGKD 1759
            |..|||..:               |..:|....||:||:..|.|.|      ..|.|:..|
 Worm   261 DQYWWQTRKIGFGALARRKESHDDENRDDSKKVGLVPSEWLQCQSE------IPENGIDTS---- 315

  Fly  1760 GSGSKGATLLCARKGRKKKKKASSEAGYPLYATTAPDETDPEEILTYEEVALYYPRATHKRPIVL 1824
               ....:.|...|||                             .||.|..:..:...:|.:||
 Worm   316 ---DDFQSFLENHKGR-----------------------------FYESVFRWRNKKKRRRVVVL 348

  Fly  1825 IGPPNIGRHELRQ---RLMADSERFSAAVPHTSRARREGEVPGVDYHFITRQAFEADILARRFVE 1886
            :|.|.:||:|:|:   ::.||  ||:.|:|||||.:|..|..||:|:|.:|...|..|..:..:|
 Worm   349 LGAPGVGRNEIRRQFFKVFAD--RFTNAIPHTSRPQRPNESDGVNYYFTSRSEMERMIERKEMLE 411

  Fly  1887 HGEYEKAYYGTSLEAIRTVVASGKICVLNLHPQSLKLLRASDLKPYVVLVAPPSLDKL------- 1944
            :||:....|||:|:::|.....|.: :|..||.:::.:|..:..|.|:.|.||...:.
 Worm   412 YGEFRDNLYGTALKSVRKASEKGTV-LLTPHPLAIENIRTWEFAPIVIFVQPPEFGEFKHTREVY 475

  Fly  1945 RQKKLRN------------------GEPFKEEELKDIIATARDMEARWGHLFDMIIINNDTERAY 1991
            |.:..|:                  ...|.:.|::.||..:..||.::....|.||.|.|.:...
 Worm   476 RSQTTRSHSAASSSNISQNTAATSAARAFSDVEIRQIIDNSAQMEQKYRGYCDAIIRNVDLDTTM 540

  Fly  1992 HQLLAEINSLEREPQWVPAQWV 2013
            ::|...|..||.:..|:|.:|:
 Worm   541 NELTGLIYQLESKATWMPMKWL 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sdt	NP_001033835.2	PDZ	<54..100	CDD:214570
		PDZ_MPP5-like	1563..1641	CDD:467259	31/78 (40%)
		SH3_MPP5	1673..1734	CDD:212969	27/75 (36%)
		GuKc	1831..2002	CDD:214504	56/198 (28%)
magu-1	NP_497201.1	PDZ_MPP3-MPP4-MPP7-like	129..208	CDD:467260	31/78 (40%)
		SH3_MPP	224..300	CDD:212796	27/75 (36%)
		Guanylate_kin	348..550	CDD:395500	59/204 (29%)