DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sdt and mpp7b

DIOPT Version :9

Sequence 1:	NP_001033835.2	Gene:	sdt / 44861	FlyBaseID:	FBgn0261873	Length:	2020	Species:	Drosophila melanogaster
Sequence 2:	XP_021324128.1	Gene:	mpp7b / 101882129	ZFINID:	ZDB-GENE-141212-293	Length:	298	Species:	Danio rerio

Alignment Length:	365	Identity:	114/365 - (31%)
Similarity:	172/365 - (47%)	Gaps:	101/365 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  1407 LQRRRSRVSGPLHHSSLGLQKDIVELLTQS-NTAAAIELGNLLTSHEMEGLLLAHDRIANHTDGT 1470
            ||:.|::...||..|:.||...:.|.|..: |:....||.|||:...::.|||.||.:|.
Zfish    14 LQKYRAQRPAPLLDSTQGLAHRLAEELQDTVNSPETTELLNLLSKPHVQTLLLVHDVVAQ----- 73

  Fly  1471 PSPTPTPTPAIGAATGSTLSSPVAGPKRNLGMVVPPPVVPPPLAQRGAMPLPRGESPPPVPMPPL 1535
                                      ||          ..|.|              ||:|
Zfish    74 --------------------------KR----------FDPRL--------------PPLP---- 84

  Fly  1536 ATMPMSMPVNLPMSACFGTLNDQN-DNIRIIQIEKSTEPLGATVRNE--GEAVVIGRIVRGGAAE 1597
                       |:..|    |::: |:|:|:.:.|:.||||||::.:  ..|:::.|::|||||:
Zfish    85 -----------PLPDC----NEEDEDSIKIVCLVKNQEPLGATIKRDESSGAIIVARVMRGGAAD 134

  Fly  1598 KSGLLHEGDEILEVNGQELRGKTVNEVCALLGAMQGTLTFLIVPAGSPPSVGVMGGTTGSQLAGL 1662
            :|||:||||.:.||||..:..|.:.|:..:|...:|.:||.:||.            |..:|
Zfish   135 RSGLIHEGDMLKEVNGVPVEDKNLQEIIPILAKSEGAVTFKVVPG------------TNEEL--- 184

  Fly  1663 GGAHRDTAVLHVRAHFDYDPEDDLYIPCRELGISFQKGDVLHVISREDPNWWQAYREGEEDQTLA 1727
              ...||.|. |||.|||||:.|..||||:.|:.||:||||.::|::|..||||.|.|:.: ..|
Zfish   185 --ETNDTQVF-VRALFDYDPQADPAIPCRDAGLEFQRGDVLQIVSQDDDTWWQARRHGDAN-LRA 245

  Fly  1728 GLIPSQSFQHQRETMK----LAIAEEAGLARSRGKDGSGS 1763
            |||||:..|.:|..::    |..:.....|.|...:|:.|
Zfish   246 GLIPSRQLQERRVMLQRPEVLFHSPRVSRAFSDNMEGNSS 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sdt	NP_001033835.2	PDZ_signaling	<54..102	CDD:238492
		L27	1423..1466	CDD:295425	16/43 (37%)
		PDZ_signaling	1562..1640	CDD:238492	33/79 (42%)
		SH3_MPP5	1673..1734	CDD:212969	34/60 (57%)
		Guanylate_kin	1820..1994	CDD:279019
		GuKc	1831..2002	CDD:214504
mpp7b	XP_021324128.1	L27	31..74	CDD:308467	16/73 (22%)
		PDZ	97..179	CDD:214570	34/81 (42%)
		SH3_MPP	192..252	CDD:212796	34/61 (56%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D245552at33208
OrthoFinder	1	1.000	-	-		FOG0000824
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920