Protein Alignment sdt and mpp4

DIOPT Version :10

• Sequence 1: NP_001033835.2
• Gene: sdt / 44861
• FlyBaseID: FBgn0261873
• Length: 2020
• Species: Drosophila melanogaster
• Sequence 2: XP_031749716.1
• Gene: mpp4 / 100495166
• XenbaseID: XB-GENE-988529
• Length: 684
• Species: Xenopus tropicalis
• Alignment Length: 804
• Identity: 198/804 - (24%)
• Similarity: 336/804 - (41%)
• Gaps: 235/804 - (29%)

  Fly  1318 PGKAVAQQQQQATLATQVVGVENEAYLPDEDQPQAEQIDGYGELIAALTRLQNQLSKSGLSTLAG 1382
            |.||....:...|:               |..|...|.:|..::   ||.:..:|.......:.|
 Frog     4 PQKATESLRMHETM---------------EMTPSGLQENGLSQV---LTMVLEELGLYYHQDVNG 50

  Fly  1383 RVSAAHSVLASASVAHVLAARTAVLQRRRSRVSGPLHHSSLGLQKDIVELLTQSNTAAAI-ELGN 1446
             :...:::|.:..:..:|...:.:.|..:.|.. |:...:..|..::|.:|.::.::|.: ||..
 Frog    51 -IGVLYNLLQAPWLQSLLKVHSCLQQYIQQRPQ-PVLPKACILSNEVVGVLRETTSSADLRELKR 113

  Fly  1447 LLTSHEMEGLLLAHDRIANHTDGTPSPTPTPTPAIGAATGSTLSSPVAGPKRNLGMVVPPPVVPP 1511
            ||.....:.||.|||.:|....                                     .||:||
 Frog   114 LLQGPHFKALLSAHDMVAQADF-------------------------------------EPVLPP 141

  Fly  1512 PLAQRGAMPLPRGESPPPVPMPPLATMPMSMPVNLPMSACFGTLNDQNDNIRIIQIEKSTEPLGA 1576
                                          :|.|:|         |..:.:||:.:.|:.:||||
 Frog   142 ------------------------------LPDNIP---------DNEEAMRIVCLVKNKQPLGA 167

  Fly  1577 TVRNE---GEAVVIGRIVRGGAAEKSGLLHEGDEILEVNGQELRGKTVNEVCALLGAMQGTLTFL 1638
            |::..   |: :::.|::.||.|::||||:.||:::||||..:.|....:|..:|...:||:.|.
 Frog   168 TIKRHEITGD-IIVARVIHGGLADRSGLLYAGDKLVEVNGVLVDGLEPEQVIQILARSEGTIVFK 231

  Fly  1639 IVPAGSPPSVGVMGGTTGSQLAGLGGAHRDTAVLHVRAHFDYDPEDDLYIPCRELGISFQKGDVL 1703
            :    ||.:...:...|               :|:|||..||.|:.|..|||.:.|:.||:|::|
 Frog   232 L----SPVNDRYISSHT---------------MLYVRAMADYWPQQDPAIPCADAGLPFQRGEIL 277

  Fly  1704 HVISREDPNWWQAYREGEEDQTLAGLIP--------------SQSF------------------- 1735
            .::.:.|..|||| |:..:....|||||              ||.|
 Frog   278 QIVDQNDSLWWQA-RKASDLGRCAGLIPSNHLLKRKQREFWWSQPFMSHSCIKASQLSTIGEEED 341

  Fly  1736 ---------------------------------------------------------QHQRETMK 1743
                                                                     |.||...:
 Frog   342 MKIEEKFVEADEETFESEELKGGNVICKFFCSVHRNSNHLVQDIYISMPQDLATIWMQPQRHNYR 406

  Fly  1744 LAIAEEAGLARSRGKDG---SGSKGATLLCARKGRKKKKKASSEAGYPLYATTAPDETDPEEILT 1805
            |....:......|.|||   :|.:.:..||.||.........|......|.|.|         ..
 Frog   407 LEYFGQEKEDEFRDKDGNIIAGFRRSMRLCRRKTLINHMSCYSRCPSNCYHTVA---------AP 462

  Fly  1806 YEEVALYYPRATHK-RPIVLIGPPNIGRHELRQRLM-ADSERFSAAVPHTSRARREGEVPGVDYH 1868
            ||||..|..|...: |.|||:||..:|.:|:|::|: .:...|.:.||||:|.::..|..|.:|.
 Frog   463 YEEVVRYQRRPCDRHRLIVLLGPSGVGVNEMRKQLIDLNPSMFKSPVPHTTRQKKTYEENGREYF 527

  Fly  1869 FITRQAFEADILARRFVEHGEYEKAYYGTSLEAIRTVVASGKICVLNLHPQSLKLLRASDLKPYV 1933
            |::::|||:.:.:..|:|:|||....||||:||::.|:.:|.||:::|.||.:..:|..:||||:
 Frog   528 FVSKEAFESMVYSHGFLEYGEYNGHMYGTSVEAVKAVLDAGMICIIDLEPQCITGVRTHELKPYI 592

  Fly  1934 VLVAPPSLDKLRQKKLRNGE---------PFKEEELKDIIATARDMEARWGHLFDMIIINNDTER 1989
            :.:.|||.:.:|..: :|..         .||||:.::|..:|:.||.::|..||.:::|::.|.
 Frog   593 IFIKPPSRNCMRYTR-KNASIFTDYYVNMKFKEEDFQEIEESAKKMEVQFGQFFDQVVVNDNLES 656

  Fly  1990 AYHQLLAEINSLEREPQWVPAQWV 2013
            |..||::.:...:.||||:||.|:
 Frog   657 ATVQLMSILRCAQDEPQWIPASWI 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sdt	NP_001033835.2	PDZ	<54..100	CDD:214570
		PDZ_MPP5-like	1563..1641	CDD:467259	29/80 (36%)
		SH3_MPP5	1673..1734	CDD:212969	27/74 (36%)
		GuKc	1831..2002	CDD:214504	61/180 (34%)
mpp4	XP_031749716.1	L27	36..84	CDD:470651	6/49 (12%)
		L27	91..139	CDD:460717	15/84 (18%)
		PDZ_MPP3-MPP4-MPP7-like	154..234	CDD:467260	29/84 (35%)
		SH3_MPP4	247..307	CDD:212967	26/60 (43%)
		Guanylate_kin	478..666	CDD:395500	67/188 (36%)