Protein Alignment sdt and pals1b

DIOPT Version :9

• Sequence 1: NP_001033835.2
• Gene: sdt / 44861
• FlyBaseID: FBgn0261873
• Length: 2020
• Species: Drosophila melanogaster
• Sequence 2: NP_001171218.2
• Gene: pals1b / 100422734
• ZFINID: ZDB-GENE-060531-2
• Length: 639
• Species: Danio rerio
• Alignment Length: 614
• Identity: 234/614 - (38%)
• Similarity: 332/614 - (54%)
• Gaps: 139/614 - (22%)

  Fly  1417 PLHHSSLGLQKDIVELLTQSNTAAAIELGNLLTSHEMEGLLLAHDRIANHTDGTPSPTPTPTPAI 1481
            ||...:..|:..:..:|..|....|.||..||||..::.|:.|||.||
Zfish   145 PLTAHAQQLRGQVESVLQSSKHTEATELTGLLTSPHLQALMEAHDCIA----------------- 192

  Fly  1482 GAATGSTLSSPVAGPKRNLGMVVPPPVVPPPLAQRGAMPLPRGESPPPVPMPPLATMPMSMPVNL 1546
                           ::.|.:.....|
Zfish   193 ---------------EQELDVDTIEAV-------------------------------------- 204

  Fly  1547 PMSACFGTLNDQND-NIRIIQIEKSTE-PLGATVRNEGEAVVIGRIVRGGAAEKSGLLHEGDEIL 1609
                      ||:: ..:::.:||..: |||.|||||.:.|||.|:|.||.||||.||.||||||
Zfish   205 ----------DQDEKTTKLVSLEKIRDIPLGVTVRNEQDCVVISRVVSGGTAEKSNLLSEGDEIL 259

  Fly  1610 EVNGQELRGKTVNEVCALLGAMQGTLTFLIVPAGSPPSVGVMGGTTGSQLAGLGGAH------RD 1668
            |:|...:||||||:|..||.:|.|:||||::|                      .:|      |.
Zfish   260 EINNIPVRGKTVNDVHDLLSSMYGSLTFLLIP----------------------NSHNKLPLDRP 302

  Fly  1669 TAVLHVRAHFDYDPEDDLYIPCRELGISFQKGDVLHVISREDPNWWQAYREGEEDQ-TLAGLIPS 1732
            | |:||:|:|.|||.:|.|:||:|||:|||:||:|||.|::|||||||||||.:|| .||||||.
Zfish   303 T-VMHVKANFSYDPSEDPYVPCKELGLSFQRGDILHVTSQDDPNWWQAYREGHDDQKPLAGLIPG 366

  Fly  1733 QSFQHQRETMKLAIAEEAGLARSRGKDGSGSKGATLLCARKGRKKKKKASSEAGYPLYATTAPDE 1797
            ::||..||.||..|.::.  ...:||         |.||.:.:|.:||.       ||......|
Zfish   367 KNFQQHREAMKKTITDKN--EEYKGK---------LWCAIRSKKHRKKL-------LYNPNKNIE 413

  Fly  1798 TDPEEILTYEEVALYYPRATHKRPIVLIGPPNIGRHELRQRLM-ADSERFSAAVPHTSRARREGE 1861
            ...|:|||||||:||......|||:.||||.|.|:.||||||: ::.|||:||||||:|:.|..|
Zfish   414 HYSEDILTYEEVSLYRQPPDRKRPVALIGPANSGQDELRQRLLSSEPERFAAAVPHTTRSPRVHE 478

  Fly  1862 VPGVDYHFITRQAFEADILARRFVEHGEYEKAYYGTSLEAIRTVVASGKICVLNLHPQSLKLLRA 1926
            |.|.:|:|::||:||:::.|.:|:|.|||....|||:.:::|.||.|||||:|.|.|:||::|.:
Zfish   479 VNGREYNFVSRQSFESELSAGKFIESGEYGNNLYGTNADSVRQVVNSGKICLLCLQPRSLQVLCS 543

  Fly  1927 SDLKPYVVLV--------APPSLDKLRQKKLRNGEPFKEEELKDIIATARDMEARWGHLFDMIII 1983
            ||||||::.:        .||..::......|..:....|::::::..||:||..:|||||..|.
Zfish   544 SDLKPYIIFIRPSPPPLSPPPPQERFSTMLARGVKKRMPEDVREMMEKAREMEDSYGHLFDTFIT 608

  Fly  1984 NNDTERAYHQLLAEINSLEREPQWVPAQW 2012
            ||:.|::..:||:.|..|:.||||:|:.|
Zfish   609 NNEPEKSVCELLSIIQKLDNEPQWIPSAW 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sdt	NP_001033835.2	PDZ_signaling	<54..102	CDD:238492
		L27	1423..1466	CDD:295425	16/42 (38%)
		PDZ_signaling	1562..1640	CDD:238492	46/78 (59%)
		SH3_MPP5	1673..1734	CDD:212969	42/61 (69%)
		Guanylate_kin	1820..1994	CDD:279019	80/182 (44%)
		GuKc	1831..2002	CDD:214504	76/179 (42%)
pals1b	NP_001171218.2	L27_N	86..133	CDD:312557
		L27	156..197	CDD:197794	15/72 (21%)
		PDZ_signaling	211..290	CDD:238492	46/78 (59%)
		SH3_MPP5	306..367	CDD:212969	42/60 (70%)
		Guanylate_kin	434..626	CDD:331880	84/191 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585851
Domainoid	1	1.000	210	1.000	Domainoid score	I2764
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D245552at33208
OrthoFinder	1	1.000	-	-		FOG0000824
OrthoInspector	1	1.000	-	-		otm26191
orthoMCL	1	0.900	-	-		OOG6_107065
Panther	1	1.100	-	-	O	PTHR23122
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4595
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.710