DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sad and si:dkey-91i10.3

DIOPT Version :9

Sequence 1:	NP_650123.1	Gene:	sad / 44858	FlyBaseID:	FBgn0003312	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001116749.1	Gene:	si:dkey-91i10.3 / 565876	ZFINID:	ZDB-GENE-081105-124	Length:	513	Species:	Danio rerio

Alignment Length:	494	Identity:	122/494 - (24%)
Similarity:	219/494 - (44%)	Gaps:	80/494 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 TLVDLIAAGGATHLH-----KYIDARH-------KQYGPIFRERLGGTQDAVFVSSANLMRGVFQ 122
            |:.||......|.|:     .|....|       |.|||:::.:.|... .|.|:||:|:..|.:
Zfish    45 TMDDLDGPSFLTSLYWLFGKGYFQTTHQMQIEHSKIYGPLWKSKYGPLV-IVNVASADLIEQVLR 108

  Fly   123 HEGQYPQHPLPDAWTLYNQQHACQRGLFFMEGAEWLHNRRILNRLLLNGNLNWMDVHIESCTRRM 187
            .||::|.......|..|.:......|.....|.||...|.|||..:|...      |:.:.|..:
Zfish   109 QEGRHPIRTDMPHWRGYRKLRNHAYGPLTEMGPEWQRIRSILNPRMLKPK------HVSNYTNAI 167

  Fly   188 VDQWKRRTAEAAAIPLAESGEIRSYELPLLEQQLYRWSIEVLCCIMFGTSVLTC--PKIQSSLDY 250
            .........:.|.:...:..::..|:   :..:||:::.|.:..::|.|. :.|  .:|......
Zfish   168 NGVVSDFIEKMAKLKTTKGNDVMVYD---VAGELYKFAFEGISSVLFETR-MGCLNDEIPEETQK 228

  Fly   251 FTQIVHKVFEHSSRLMTFPPRLAQILRLPIWRDFEANVDEVLREGAAIIDHCIRVQEDQRRPHDE 315
            |...|.::|..|..::.||..|...  :|.|:.|           .|:.||..:|.::..:....
Zfish   229 FIFSVGEMFRLSPIVILFPKFLWPY--MPFWKHF-----------VAVWDHLFKVADELVQQKMT 280

  Fly   316 ALYHRLQ-AADVPGDMIKRIFV--------------DLVIAAGDTTAFSSQWALFALSKEPRLQQ 365
            .:..::: .:.|.|:.:..:.:              :|::|..|||:.:..|||:.|::||.:||
Zfish   281 EIQEKVKTGSPVEGEYLTHLLISEQMSFTEVLGSITELLLAGVDTTSNTISWALYHLAREPEIQQ 345

  Fly   366 RLAKE----------RATND---SRLMHGLIKESLRLYPVAPFIGRYLPQ-DAQLGGHFIEKDTM 416
            :|.:|          .:::|   ..|:..:::|:||||||.|...|.:.: :..:|.|...|:|:
Zfish   346 KLHEEVVSVCPGDKTPSSDDITRMPLLKAIVRETLRLYPVVPGNARVVAENEIVVGDHLFPKNTL 410

  Fly   417 VLLSLYTAGRDPSHFEQPERVLPERWCIGETEQVHK-SHGSLPFAIGQRSCIGRRVALKQLHSLL 480
            ..|..:....|.:.|..|...||:|| |.|.:|:.: ..||:||..|.|:|:|||||..:::.||
Zfish   411 FHLCHFAVSYDETVFPDPFAFLPQRW-IREQKQLSQHPFGSVPFGFGIRACLGRRVAELEMYLLL 474

  Fly   481 GRCAAQFEMSCLNEMP------VDSVLRMVTVPDRTLRL 513
            .|...::|:     .|      |..:.|.:.||..::.|
Zfish   475 SRLIKRYEV-----RPDPSGKTVKPITRTLLVPATSIDL 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sad	NP_650123.1	p450	63..497	CDD:299894	117/476 (25%)
si:dkey-91i10.3	NP_001116749.1	p450	52..510	CDD:278495	119/487 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592739
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48087
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.760