Protein Alignment sad and cyp4v2a

DIOPT Version :10

• Sequence 1: NP_650123.1
• Gene: sad / 44858
• FlyBaseID: FBgn0003312
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001071070.1
• Gene: cyp4v2a / 558851
• ZFINID: ZDB-GENE-061103-601
• Length: 513
• Species: Danio rerio
• Alignment Length: 532
• Identity: 123/532 - (23%)
• Similarity: 210/532 - (39%)
• Gaps: 149/532 - (28%)

  Fly    81 THLHKYIDARHKQYGPIFRERLGGTQDAV-----FVSSANLMRGVFQHEGQYPQHPLPDAWTLYN 140
            ::|||:     |:..||  ..:|.|...:     |.|:.:....:..:..::...||...|.
Zfish    32 SYLHKW-----KELKPI--PGIGNTFPFIGNALQFKSNGDFFLQLVGYTTEFQNSPLLKIWI--- 86

  Fly   141 QQHACQRG------LFFMEGAEWLHNRRI-LNRLLLNGNLN-WMDVHIESCTRRMVDQWKRR--- 194
                   |      ||..|..|.:.|..: :::......|: |:...:.:.|.   |:|:||
Zfish    87 -------GPIPFLILFHAETVETVLNNPVHIDKAYAYQFLHPWLGTGLLTSTG---DKWRRRRKM 141

  Fly   195 -TAEAAAIPLAESGEIRSYELPLLEQQLYR---------------WSIEVLCCIMFGTSVLTCPK 243
             |.......|.|..|:.:.:..:|.::|.:               .:::::|....|      .:
Zfish   142 LTPTFHFSILTEFLEVMNEQAEVLIEKLEKQAGKGPFNCFSHITLCALDIICETAMG------KR 200

  Fly   244 IQSSLDYFTQIVHKVFEHSSRLMTFPPRLAQIL----RLP-IWRDFEAN---------------- 287
            |.:..:|.::.|..|:           |::.|:    |:| .|.||..|
Zfish   201 IYAQSNYDSEYVRTVY-----------RMSDIITRRQRMPWYWPDFVYNYVGEGREHNRSLKILH 254

  Fly   288 --VDEVLREGAAIIDHCIRVQEDQRRPHDEALYHR-------LQAADVPGDMI--KRI--FVDLV 339
              .:.|:.|.|..:.:   |:.|..  .|:.:..|       |:..|..|.|:  |.|  .||..
Zfish   255 SFTESVINERAEYLSY---VESDSE--SDQGMRKRRAFLDMLLKTKDEDGKMLTHKDIQEEVDTF 314

  Fly   340 IAAG-DTTAFSSQWALFALSKEPRLQQRLAK---------ERATNDS-----RLMHGLIKESLRL 389
            :..| ||||.:..||:..|...|.:|::..:         ||..|..     |.:..:|||||||
Zfish   315 MFEGHDTTAAAMNWAIHLLGSHPEVQRKAQQELFEVFGESERPVNTEDLKKLRYLECVIKESLRL 379

  Fly   390 YPVAPFIGRYLPQDAQLGGHFIEKDTMVLLSLYTAGRDPSHFEQPERVLPERW----CIGETEQV 450
            :|..||..|.:..|.|:.|..:.|.|.:::..|...|||..|..||...|||:    |:|
Zfish   380 FPSVPFFARTICDDTQINGFKVPKGTNIVVITYALHRDPRFFPDPEEFRPERFLPENCVG----- 439

  Fly   451 HKSHGSLPFAIGQRSCIGRRVALKQLHSLLG---------RCAAQFEMSCLNEMPVDSVLRMVTV 506
            ...:..:||:.|.|:|||:|.|:.:...:|.         .|..:.|:..|.|:    |||
Zfish   440 RHPYAYIPFSAGLRNCIGQRFAIMEEKVILAYILRYFNIVACQKREELRPLGEL----VLR---- 496

  Fly   507 PDRTLRLALRPR 518
            |::.:.:.|..|
Zfish   497 PEQGIWITLERR 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sad	NP_650123.1	CYP24A1-like	91..512	CDD:410677	118/514 (23%)
cyp4v2a	NP_001071070.1	cytochrome_P450	68..503	CDD:477761	111/482 (23%)