Protein Alignment sad and Cyp24a1

DIOPT Version :10

• Sequence 1: NP_650123.1
• Gene: sad / 44858
• FlyBaseID: FBgn0003312
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_963966.1
• Gene: Cyp24a1 / 25279
• RGDID: 2462
• Length: 514
• Species: Rattus norvegicus
• Alignment Length: 537
• Identity: 148/537 - (27%)
• Similarity: 235/537 - (43%)
• Gaps: 63/537 - (11%)

  Fly    18 LDQLLVRILSLSLFRSRCDPPPLQRFPATELPPAVAAKYVP---------------IPRVKGLPV 67
            :|:....|..|...|....||   |...::...:.|.|.||               :|.....|:
  Rat     5 IDKRRTLIAFLRRLRDLGQPP---RSVTSKASASRAPKEVPLCPLMTDGETRNVTSLPGPTNWPL 66

  Fly    68 VGTLVDLIAAGGATHLHKYIDARHKQYGPIFRERLGGTQDAVFVSSANLMRGVFQHEGQYPQHPL 132
            :|:|:::...||....|..:...||:||.|||.:| |:.|:|.:.|.:|:..:::.|..:||...
  Rat    67 LGSLLEIFWKGGLKKQHDTLAEYHKKYGQIFRMKL-GSFDSVHLGSPSLLEALYRTESAHPQRLE 130

  Fly   133 PDAWTLYNQQHACQRGLFFMEGAEWLHNRRILNRLLLNGNLNWMDVHIESCTRR---MVDQWKRR 194
            ...|..|........||..:||.||...|....:.|:.      .|.|....::   ::..:..|
  Rat   131 IKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMK------PVEIMKLDKKINEVLADFLER 189

  Fly   195 TAEAAAIPLAESGEIRSYELPLLEQQLYRWSIEVLCCIM----FGTSVLTCPKIQSSLDYFTQIV 255
            ..|..    .|.|.|     |.|..:|.:||.|.:|.::    ||  :|.....:.:|.:.|.|
  Rat   190 MDELC----DERGRI-----PDLYSELNKWSFESICLVLYEKRFG--LLQKETEEEALTFITAI- 242

  Fly   256 HKVFEHSSRLMTFPPRLAQILRLPIWRDFEANVDEVLREGAAIIDHCIRVQEDQRRPHDEALYHR 320
            ..:.....::|..|..|.:.|...:|:......|.:.:.....||:  |:|...::|..:.|...
  Rat   243 KTMMSTFGKMMVTPVELHKRLNTKVWQAHTLAWDTIFKSVKPCIDN--RLQRYSQQPGADFLCDI 305

  Fly   321 LQAADVPGDMIKRIFVDLVIAAGDTTAFSSQWALFALSKEPRLQQRLAKE-----------RATN 374
            .|...:....:.....:|.:||.:|||.|..|.|:.||:.|:.|:||.:|           || .
  Rat   306 YQQDHLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQAQRRLLQEVQSVLPDNQTPRA-E 369

  Fly   375 DSRLMHGL---IKESLRLYPVAPFIGRYLPQDAQLGGHFIEKDTMVLLSLYTAGRDPSHFEQPER 436
            |.|.|..|   :|||:||.|..||..|.|.:...||.:.:.|.|::.|:....|....:||...:
  Rat   370 DLRNMPYLKACLKESMRLTPSVPFTTRTLDKPTVLGEYALPKGTVLTLNTQVLGSSEDNFEDSHK 434

  Fly   437 VLPERWCIGETEQVHKSHGSLPFAIGQRSCIGRRVALKQLHSLLGRCAAQFEMSCLNEMPVDSVL 501
            ..||||.  :.|:.......|||.||:|.|||||:|..|||..|.....::::...:..||:.:.
  Rat   435 FRPERWL--QKEKKINPFAHLPFGIGKRMCIGRRLAELQLHLALCWIIQKYDIVATDNEPVEMLH 497

  Fly   502 RMVTVPDRTLRLALRPR 518
            ..:.||.|.|.:|.|||
  Rat   498 LGILVPSRELPIAFRPR 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sad	NP_650123.1	CYP24A1-like	91..512	CDD:410677	125/441 (28%)
Cyp24a1	NP_963966.1	CYP24A1	90..508	CDD:410738	125/441 (28%)