Protein Alignment sad and Cyp11b2

DIOPT Version :10

• Sequence 1: NP_650123.1
• Gene: sad / 44858
• FlyBaseID: FBgn0003312
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_036670.2
• Gene: Cyp11b2 / 24294
• RGDID: 2454
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 500
• Identity: 136/500 - (27%)
• Similarity: 224/500 - (44%)
• Gaps: 61/500 - (12%)

  Fly    48 LPPAVAAKYVPIP---RVKGLPVVGTLVDLIAAGGATHLHKYIDARHKQYGPIFRERLGGTQDAV 109
            |.|.....:..||   |.|.|    .::.::...|..:||..:....::.|||||...||.| .|
  Rat    32 LAPKTLKPFEAIPQYSRNKWL----KMIQILREQGQENLHLEMHQAFQELGPIFRHSAGGAQ-IV 91

  Fly   110 FVSSANLMRGVFQHEGQYPQHPLPDAWTLYNQQHACQRGLFFMEGAEWLHNRRILNRLLLNGNL- 173
            .|........:.|.|...|:....:.|..:.:....:||:|.:.||:|.     .|||.||.|:
  Rat    92 SVMLPEDAEKLHQVESILPRRMHLEPWVAHRELRGLRRGVFLLNGADWR-----FNRLKLNPNVL 151

  Fly   174 ------NWMDVHIESCTRRMVDQWKRRTAEAAAIPLAESGEIRSYELPLLEQQLYRWSIEVLCCI 232
                  |::.: ::...|..::..|::..:.|...|...          ::|.|:.::||.....
  Rat   152 SPKAVQNFVPM-VDEVARDFLEALKKKVRQNARGSLTMD----------VQQSLFNYTIEASNFA 205

  Fly   233 MFGTSV-LTCPKIQSSLDYFTQIVHKVFEHSSRLMTFPPRLAQILRLPIWRD-FEANVDEVLREG 295
            :||..: |....:......|...:|.:|:.:::|:..|..|.:.....:|:: |:|  .:|:.|.
  Rat   206 LFGERLGLLGHDLNPGSLKFIHALHSMFKSTTQLLFLPRSLTRWTSTRVWKEHFDA--WDVISEY 268

  Fly   296 AAIIDHCIRVQEDQRRPHDEALYHRLQAA-----DVPGDMIKRIFVDLVIAAGDTTAFSSQWALF 355
            |   :.||.....:.|......|..:.||     .:|.|.||...::|...:.||||......||
  Rat   269 A---NRCIWKVHQELRLGSSQTYSGIVAALITQGALPLDAIKANSMELTAGSVDTTAIPLVMTLF 330

  Fly   356 ALSKEPRLQQRLAKE-------------RATNDSRLMHGLIKESLRLYPVAPFIGRYLPQDAQLG 407
            .|::.|.:||.|.:|             :|.:|..|:...:||:||||||..|:.|.|..|..|.
  Rat   331 ELARNPDVQQALRQETLAAEASIAANPQKAMSDLPLLRAALKETLRLYPVGGFLERILNSDLVLQ 395

  Fly   408 GHFIEKDTMVLLSLYTAGRDPSHFEQPERVLPERWCIGETEQVHKSHGSLPFAIGQRSCIGRRVA 472
            .:.:...|:|||.||:.||:|:.|.:|||.:|:||.     :..:|...|.|..|.|.|:|||:|
  Rat   396 NYHVPAGTLVLLYLYSMGRNPAVFPRPERYMPQRWL-----ERKRSFQHLAFGFGVRQCLGRRLA 455

  Fly   473 LKQLHSLLGRCAAQFEMSCLNEMPVDSVLRMVTVPDRTLRLALRP 517
            ..::..||......|::..|.:..|....|.|.:|..:..|..||
  Rat   456 EVEMLLLLHHMLKTFQVETLRQEDVQMAYRFVLMPSSSPVLTFRP 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sad	NP_650123.1	CYP24A1-like	91..512	CDD:410677	123/447 (28%)
Cyp11b2	NP_036670.2	cytochrome_P450	74..498	CDD:477761	124/450 (28%)