Protein Alignment sad and CYP11A1

DIOPT Version :9

• Sequence 1: NP_650123.1
• Gene: sad / 44858
• FlyBaseID: FBgn0003312
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_000772.2
• Gene: CYP11A1 / 1583
• HGNCID: 2590
• Length: 521
• Species: Homo sapiens
• Alignment Length: 459
• Identity: 111/459 - (24%)
• Similarity: 209/459 - (45%)
• Gaps: 43/459 - (9%)

  Fly    82 HLHKYIDARHKQYGPIFRERLGGTQDAVFVSSANLMRGVFQHEGQYPQHPLPDAWTLYNQQHACQ 146
            |||..  ...::||||:||:||.. ::|:|.....:..:|:.||..|:..|...|..|:|.:...
Human    75 HLHHV--QNFQKYGPIYREKLGNV-ESVYVIDPEDVALLFKSEGPNPERFLIPPWVAYHQYYQRP 136

  Fly   147 RGLFFMEGAEWLHNRRILNRLLL--NGNLNWMDVHIESCTRRMVDQWKRRTAEAAAIPLAESGEI 209
            .|:...:.|.|..:|..||:.::  ....|::.: :::.:|..|....||..:|.:...  ||:|
Human   137 IGVLLKKSAAWKKDRVALNQEVMAPEATKNFLPL-LDAVSRDFVSVLHRRIKKAGSGNY--SGDI 198

  Fly   210 RSYELPLLEQQLYRWSIEVLCCIMFG-----TSVLTCPKIQSSLDYFTQIVHKVFEHSSRLMTFP 269
                    ...|:|::.|.:..::||     ...:..|:.|..:|    .::::|..|..::..|
Human   199 --------SDDLFRFAFESITNVIFGERQGMLEEVVNPEAQRFID----AIYQMFHTSVPMLNLP 251

  Fly   270 PRLAQILRLPIWRDFEANVDEVLREGAAIIDHC---IRVQEDQRRPHDEALYHRLQAADVPGDMI 331
            |.|.::.|...|:|..|..|.:..:......:.   :|.:......:...||..|..:.:..:.|
Human   252 PDLFRLFRTKTWKDHVAAWDVIFSKADIYTQNFYWELRQKGSVHHDYRGILYRLLGDSKMSFEDI 316

  Fly   332 KRIFVDLVIAAGDTTAFSSQWALFALSKEPRLQQRL------AKERATNDSR-------LMHGLI 383
            |....:::....|||:.:.||.|:.:::..::|..|      |:.:|..|..       |:...|
Human   317 KANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKASI 381

  Fly   384 KESLRLYPVAPFIGRYLPQDAQLGGHFIEKDTMVLLSLYTAGRDPSHFEQPERVLPERWCIGETE 448
            ||:|||:|::..:.|||..|..|..:.|...|:|.:::|..||:|:.|..||...|.||...:..
Human   382 KETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKN 446

  Fly   449 QVHKSHGSLPFAIGQRSCIGRRVALKQLHSLLGRCAAQFEMSCLNEMPVDSVLRMVTVPDRTLRL 513
            ..:  ..:|.|..|.|.|:|||:|..::...|......|.:...:...|.:...::.:|::.:..
Human   447 ITY--FRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRVEIQHLSDVGTTFNLILMPEKPISF 509

  Fly   514 ALRP 517
            ...|
Human   510 TFWP 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sad	NP_650123.1	p450	63..497	CDD:299894	108/437 (25%)
CYP11A1	NP_000772.2	p450	52..511	CDD:278495	110/455 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_110753
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.720