Protein Alignment sad and Cyp27b1

DIOPT Version :10

• Sequence 1: NP_650123.1
• Gene: sad / 44858
• FlyBaseID: FBgn0003312
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_034139.2
• Gene: Cyp27b1 / 13115
• MGIID: 1098274
• Length: 507
• Species: Mus musculus
• Alignment Length: 488
• Identity: 140/488 - (28%)
• Similarity: 215/488 - (44%)
• Gaps: 61/488 - (12%)

  Fly    62 VKGLPVVGTLVDLIAAGGATHLHKYIDARHKQYGPIFRERLGGTQDAVFVSSANLMRGVFQHEGQ 126
            :.|...:..|.:|...||.:.||:.......:||||:.... ||...|:|:...|:..:.:.|..
Mouse    40 IPGPSTLSFLAELFCKGGLSRLHELQVHGAARYGPIWSGSF-GTLRTVYVADPTLVEQLLRQESH 103

  Fly   127 YPQHPLPDAWTLYNQQHACQRGLFFMEGAEWLHNRRILNRLLLN-----GNLNWMDVHIESCTRR 186
            .|:.....:|..:.::|....||...:|.||...|.:|..|||.     |....:|..:....||
Mouse   104 CPERCSFSSWAEHRRRHQRACGLLTADGEEWQRLRSLLAPLLLRPQAAAGYAGTLDNVVRDLVRR 168

  Fly   187 MVDQWKRRTAEAAAIP---LAESGEIRSYELPLLEQQLYRWSIEVLCCIMFGTSVLTC--PKIQS 246
            :    :|:....:.:|   |..:||            .|::.:|.:..::.| |.|.|  .::..
Mouse   169 L----RRQRGRGSGLPGLVLDVAGE------------FYKFGLESIGAVLLG-SRLGCLEAEVPP 216

  Fly   247 SLDYFTQIVHKVFEHSSRLMTFPPRLAQILRLPIW----RDFE-----ANVDEVLREGAAIIDHC 302
            ..:.|...|..||..:...|..|..|..::..| |    ||::     |.....||||.|.:.:.
Mouse   217 DTETFIHAVGSVFVSTLLTMAMPNWLHHLIPGP-WARLCRDWDQMFAFAQRHVELREGEAAMRNQ 280

  Fly   303 IRVQEDQRRPHDEALYHRLQAADVPGDMIKRIFVDLVIAAGDTTAFSSQWALFALSKEPRLQQRL 367
            .:.:||.  |....|.|.|....|....|.....:|::|..||.:.:..|.|:.||:.|.:|..|
Mouse   281 GKPEEDM--PSGHHLTHFLFREKVSVQSIVGNVTELLLAGVDTVSNTLSWTLYELSRHPDVQTAL 343

  Fly   368 AKE--------------RATNDSRLMHGLIKESLRLYPVAPFIGRYLPQDAQLGGHFIEKDTMVL 418
            ..|              .|.:...|:..:|||.||||||.|...|...:|.::|.:.|.:||:|.
Mouse   344 HSEITAGTRGSCAHPHGTALSQLPLLKAVIKEVLRLYPVVPGNSRVPDRDIRVGNYVIPQDTLVS 408

  Fly   419 LSLYTAGRDPSHFEQPERVLPERWCIGETEQVHKSHGSLPFAIGQRSCIGRRVALKQLHSLLGRC 483
            |..|...|||:.|..|....|.|| :||....| ...||||..|:|||||||:|..:|...|.:.
Mouse   409 LCHYATSRDPTQFPDPNSFNPARW-LGEGPTPH-PFASLPFGFGKRSCIGRRLAELELQMALSQI 471

  Fly   484 AAQFEMSCLNE---MPVDSVLRMVTVPDRTLRL 513
            ...||:  |.|   :|:..:.|.|.||:|::.|
Mouse   472 LTHFEV--LPEPGALPIKPMTRTVLVPERSINL 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sad	NP_650123.1	CYP24A1-like	91..512	CDD:410677	132/456 (29%)
Cyp27b1	NP_034139.2	CYP27B1	68..502	CDD:410741	132/458 (29%)