Protein Alignment sad and shd

DIOPT Version :10

• Sequence 1: NP_650123.1
• Gene: sad / 44858
• FlyBaseID: FBgn0003312
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_061508318.1
• Gene: shd / 1273531
• VectorBaseID: AGAMI1_008101
• Length: 577
• Species: Anopheles gambiae
• Alignment Length: 547
• Identity: 129/547 - (23%)
• Similarity: 218/547 - (39%)
• Gaps: 128/547 - (23%)

  Fly    44 PATELPPAVAAKYVP-------IPRVKGLPVVGTLVDLIAAGGATHLHKYIDAR------HKQYG 95
            ||...||..|.  ||       ||..:.||::||.......     .|:|....      |::||
Mosquito    88 PAPSPPPNDAG--VPTVRSIWDIPGPRRLPLIGTKWRYFFG-----RHRYAKVHETFMEMHRRYG 145

  Fly    96 PIFRERLGGTQDAVFVSSANL-----MRGVFQHEGQYPQHPLPDAWTLYNQQHACQRG---LFFM 152
            ||.       .|...|...||     |..|.::..:||..|..:...:|......:.|   |...
Mosquito   146 PIM-------LDVDTVPIVNLFDRADMEKVLRYPSRYPFRPPTEIVEVYRSSRPDRFGVTNLINA 203

  Fly   153 EGAEW----------LHNRRILNRLLLNGNLNWMDVHIESCTRRMVDQWKRRTAEAAAIPLAESG 207
            :||:|          :.:||:|...:.:.|        |.|. ..||..:|:.        |:.|
Mosquito   204 QGAKWHELRAKLTTGITSRRVLQAFIPSVN--------EICD-DFVDLVRRQR--------ADDG 251

  Fly   208 EIRSYELPLLEQQLYRWSIEVLCCIMFGTSV--LTCPKIQSSLDYFTQIVHKVFEHSSRLMTFPP 270
            .||::     :.......:|::||::.|..:  ||..:..:......:.|.:.|.:... ..|..
Mosquito   252 TIRNF-----QDIANSVGLEIICCLVLGRRMGYLTTNRQNAKFMRLAEAVKESFVYIGE-SYFGL 310

  Fly   271 RLAQILRLPIWRDFEANVDEVLREGAAIIDHCIRVQEDQRRPHDEALYHRLQAADV--PGDMIKR 333
            :|.:.:...::.:| ...:|::.|..|                 |.:|..|:...:  |.:.:|.
Mosquito   311 KLWKYVPTRLYSNF-VRCEEIIYETIA-----------------EIVYEALEEEQLNCPDNDVKH 357

  Fly   334 IF------------------VDLVIAAGDTTAFSSQWALFALSKEPRLQQRLAKERA------TN 374
            ||                  :||:.:|.:|.:.:..:.|..||:....|:.:|.|.|      ||
Mosquito   358 IFISILQTEGLDTKEKISGIIDLITSAIETLSNTLSFLLHNLSQTVEYQREIAHEFAHCVQHITN 422

  Fly   375 D----SRLMHGLIKESLRLYPVAPFIGRYLPQDAQLGGHFIEKDTMVLLSLYTAGRDPSHFEQPE 435
            :    :|.....|:||.|:.|..|.:.|.|.:|.||.|:.::..|:||.....|.....:|:|.:
Mosquito   423 EDLVSARFTKACIQESYRISPTTPCLARILEEDFQLSGYHLQAGTLVLCHTRVACLSEDNFQQAD 487

  Fly   436 RVLPERWCIGETEQ---VHK--SHGS---LPFAIGQRSCIGRRVALKQLHSLLGRCAAQFEMSCL 492
            |.||:||.....|.   |:|  ..|:   |||.||:|.|.|::|...:|..|:.:....||:.
Mosquito   488 RFLPDRWLEQRDENDNVVNKRAEPGASVVLPFGIGRRMCPGQKVIDIELTLLVAKIFQNFEIE-- 550

  Fly   493 NEMPVDSVLRMVTVPDRTLRLALRPRT 519
            ...|:|:..:.:..|...:.:..|.||
Mosquito   551 YRSPLDTQFQFLLAPRTPIEIRFRDRT 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sad	NP_650123.1	CYP24A1-like	91..512	CDD:410677	111/478 (23%)
shd	XP_061508318.1	None