Protein Alignment sad and Cyp11b1

DIOPT Version :10

• Sequence 1: NP_650123.1
• Gene: sad / 44858
• FlyBaseID: FBgn0003312
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001028401.3
• Gene: Cyp11b1 / 110115
• MGIID: 88583
• Length: 499
• Species: Mus musculus
• Alignment Length: 501
• Identity: 127/501 - (25%)
• Similarity: 229/501 - (45%)
• Gaps: 55/501 - (10%)

  Fly    37 PPPLQRFPATELPPAVAAKYVPIPRVKGLPVVGTLVDLIAAGGATHLHKYIDARHKQYGPIFRER 101
            |..||.|.|  :|.....|::            .::.::...|..:||..:....::.|||||..
Mouse    32 PKTLQPFEA--IPQYSRNKWL------------KMIQILREQGQENLHLEMHQVFRELGPIFRHS 82

  Fly   102 LGGTQDAVFVSSANLMRGVFQHEGQYP-QHPLPDAWTLYNQQHACQRGLFFMEGAEWLHNRRILN 165
            :|.|| .|||:....:..::|.|..:| :.|| ::|.::.:.....||:|.:.|.||..||..||
Mouse    83 VGKTQ-IVFVTLPEDVEKLYQVESTHPCRMPL-ESWIVHRELRGLGRGVFLLNGPEWYFNRLQLN 145

  Fly   166 RLLLNGNLNWMDVH-IESCTRRMVDQWKRRTAEAAAIPLAESGEIRSYELPLLEQQLYRWSIEVL 229
            ..:|:.......|. ::...|..||..|::..|:..         .|:.:. .:..::.::||..
Mouse   146 PNVLSPKAVQKFVPLVDGIARDFVDNLKKKMLESVH---------GSFSMD-FQSSVFNYTIEAS 200

  Fly   230 CCIMFGTSV-LTCPKIQSSLDYFTQIVHKVFEHSSRLMTFPPRLAQILRLPIWRDFEANVDEVLR 293
            ..::||..: |....:......|...:|.:|:.:::|:..|..|.:.....:|::...:.|.:
Mouse   201 HFVLFGERLGLIGRDLSPDSLKFLHTLHSMFKTTTQLLYLPRSLTRWTSTRVWKENLESWDFI-- 263

  Fly   294 EGAAIIDHCIR-VQED--QRRPHDEALYHRLQA-ADVPGDMIKRIFVDLVIAAGDTTAFSSQWAL 354
              :..:..||: |..:  :.||...::...|.| ..:..|.|:...::|:..:.|||:.......
Mouse   264 --SEYVTKCIKNVYRELAEGRPQSWSVTAELVAERTLSMDAIQANSMELIAGSTDTTSTPLVMTF 326

  Fly   355 FALSKEPRLQQRLAKE-------------RATNDSRLMHGLIKESLRLYPVAPFIGRYLPQDAQL 406
            |.|::.|.:||.|.:|             :|.:|..|:...:||:||||||..|:.|.|..|..|
Mouse   327 FELARNPDVQQALRQESLAAEASIAANPQKAMSDLPLLRAALKETLRLYPVGTFLERILSSDLVL 391

  Fly   407 GGHFIEKDTMVLLSLYTAGRDPSHFEQPERVLPERWCIGETEQVHKSHGSLPFAIGQRSCIGRRV 471
            ..:.:...|::.::||:.||:|:.|.:|||.:|:||.     :..:|...|.|..|.|.|:|||:
Mouse   392 QNYHVPAGTVLNVNLYSMGRNPAVFPRPERYMPQRWL-----ERKRSFKHLAFGFGVRQCLGRRL 451

  Fly   472 ALKQLHSLLGRCAAQFEMSCLNEMPVDSVLRMVTVPDRTLRLALRP 517
            |..::..||......|.:....:..|....|.|.:|..:..|..||
Mouse   452 AEAEMMLLLHHVLKSFHVETQEKEDVRMAYRFVLMPSSSPLLTFRP 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sad	NP_650123.1	CYP24A1-like	91..512	CDD:410677	114/440 (26%)
Cyp11b1	NP_001028401.3	cytochrome_P450	72..495	CDD:477761	115/443 (26%)