DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sad and Cyp4v3

DIOPT Version :9

Sequence 1:	NP_650123.1	Gene:	sad / 44858	FlyBaseID:	FBgn0003312	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_598730.1	Gene:	Cyp4v3 / 102294	MGIID:	2142763	Length:	525	Species:	Mus musculus

Alignment Length:	441	Identity:	96/441 - (21%)
Similarity:	181/441 - (41%)	Gaps:	120/441 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 GLFFMEGAEWLHNRRIL----NRLLLNGNLNWMDVHIESCTRRMVDQWKRRTAEAA-----AIPL 203
            ||....|::|...|::|    :..:|.   |::||..|. ...:|::.::...:.|     .|.|
Mouse   134 GLLTSTGSKWRTRRKMLTPTFHFTILE---NFLDVMNEQ-ANILVNKLEKHVNQEAFNCFFYITL 194

  Fly   204 AESGEIRSYELPLLEQQLYRWSIEVLCCIMFGTSVLTCPKIQSSLDYFTQIVHKVFEHSSRLMTF 268
            .                    :::::|....|.::    ..||:.|  ::.|..|:..|..:.
Mouse   195 C--------------------ALDIICETAMGKNI----GAQSNND--SEYVRTVYRMSDMIY-- 231

  Fly   269 PPRLAQILRLP-IWRDFEANVDEVLREGAAIIDH-----CI----------RVQEDQRRPHDEAL 317
                 :.:::| :|.|...   .|.:||.   ||     |:          ||:|  |:..::
Mouse   232 -----RRMKMPWLWFDLWY---LVFKEGR---DHKRGLKCLHTFTNNVIAERVKE--RKAEED-- 281

  Fly   318 YHRLQAADVPGDMIKRIFVDLVIA------------------------AGDTTAFSSQWALFALS 358
            :.......:|....::.|:||:::                        ..||||.:..|:|:.|.
Mouse   282 WTGAGRGPIPSKNKRKAFLDLLLSVTDEEGNRLSQEDIREEVDTFMFEGHDTTAAAINWSLYLLG 346

  Fly   359 KEPRLQQRLAKE--------------RATNDSRLMHGLIKESLRLYPVAPFIGRYLPQDAQLGGH 409
            ..|.:|:::.:|              ......:.:..:|||:||::|..|...|.|.:|.::||:
Mouse   347 TNPEVQRKVDQELDEVFGRSHRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVGGY 411

  Fly   410 FIEKDTMVLLSLYTAGRDPSHFEQPERVLPERWCIGETEQVHKSHGSLPFAIGQRSCIGRRVALK 474
            .:.|.|..::..|...|||.:|..||...|||: ..|..|....:..:||:.|.|:|||::.|:.
Mouse   412 KVTKGTEAIIIPYALHRDPRYFPDPEEFRPERF-FPENSQGRHPYAYVPFSAGPRNCIGQKFAVM 475

  Fly   475 QLHSLLGRCAAQF--EMSCLNE---MPVDSVLRMVTVPDRTLRLALRPRTE 520
            :..::|.....||  |.:...|   :..|.:||    |:..:.:.|:.|.|
Mouse   476 EEKTILACILRQFWVESNQKREELGLAGDLILR----PNNGIWIKLKRRHE 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sad	NP_650123.1	p450	63..497	CDD:299894	89/416 (21%)
Cyp4v3	NP_598730.1	p450	51..517	CDD:278495	93/434 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010