Protein Alignment sad and cyp24a1

DIOPT Version :10

• Sequence 1: NP_650123.1
• Gene: sad / 44858
• FlyBaseID: FBgn0003312
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_012808417.2
• Gene: cyp24a1 / 100497429
• XenbaseID: XB-GENE-479201
• Length: 508
• Species: Xenopus tropicalis
• Alignment Length: 528
• Identity: 134/528 - (25%)
• Similarity: 234/528 - (44%)
• Gaps: 61/528 - (11%)

  Fly    21 LLVRILSLSLFRS------RCD------PPPLQRFPATELPPAVAAKYVPIPRVKGLPVVGTLVD 73
            :|::..|:|:..|      .||      |.|      :..|.::||    :|....||::|:|:|
 Frog    12 MLLKSRSISVQHSIPTATAVCDLKEEELPAP------SSCPHSLAA----LPGPTKLPILGSLLD 66

  Fly    74 LIAAGGATHLHKYIDARHKQYGPIFRERLGGTQDAVFVSSANLMRGVFQHEGQYPQHPLPDAWTL 138
            ::..||....|:.:.:.|||:|.|||.:| |:.|:|.:.:..|:..:::.|..||:......|..
 Frog    67 ILRKGGLKRQHEALASYHKQFGKIFRMKL-GSFDSVHIGAPCLLEALYREESNYPKRLEIKPWKA 130

  Fly   139 YNQQHACQRGLFFMEGAEWLHNRRILNRLLLN-GNLNWMDVHIESCTRRMVDQWKRRTAEAAAIP 202
            |........||..:||.:|...|....:.|:. ..:..:|..|...   :||..||..:..
 Frog   131 YRDYRDEAYGLLILEGKDWQRVRSAFQQKLMKPTEVGKLDTKINEV---LVDFMKRIDSVC---- 188

  Fly   203 LAESGEIRSYELPLLEQQLYRWSIEVLCCIM----FGTSVLTCPKIQSSLDYFTQIVHKVFEHSS 263
             .|.|.|..     |..:|.:||:|.:|.::    ||   ...|.:......|...:..:.....
 Frog   189 -DEDGTIED-----LYCELNKWSLESICLVLYEKRFG---FLQPNLGEEAQNFITAIKMMMSTFG 244

  Fly   264 RLMTFPPRLAQILRLPIWRDFEANVDEVLREGAAIIDHCIRVQEDQRRPHDEALYHRLQAADVPG 328
            .:|..|..|.:.|...||:|.....|.:.:.....||.  |:.:...:..::.|......:.:..
 Frog   245 LMMVTPVELHKSLNTKIWKDHTHAWDSIFKTAKCHIDR--RLTKLSSKGSEDFLCTIYNDSKLSK 307

  Fly   329 DMIKRIFVDLVIAAGDTTAFSSQWALFALSKEPRLQQRLAKE----------RATNDSRLMHGL- 382
            ..:.....:::|.|.:|||.|..||:|.:|:.|.:|::|.:|          ...:|.|.|..|
 Frog   308 KEMYATITEMLIGAVETTANSLLWAIFNISRNPHIQKKLLEEIESVLLPDQVPTADDIRNMPYLK 372

  Fly   383 --IKESLRLYPVAPFIGRYLPQDAQLGGHFIEKDTMVLLSLYTAGRDPSHFEQPERVLPERWCIG 445
              :|||:|:.|..||..|.|.::..||.:.:.|.|::.::.:..|.:...|:...:..||||.
 Frog   373 ACLKESMRITPSIPFTTRTLDKETVLGDYVLPKGTVLTINSHVLGSNQECFDNWNQFRPERWL-- 435

  Fly   446 ETEQVHKSHGSLPFAIGQRSCIGRRVALKQLHSLLGRCAAQFEMSCLNEMPVDSVLRMVTVPDRT 510
            :.:........:||.||:|.|||||:|..||...|.....::|:...:..||:::.....:|.|.
 Frog   436 QQKNTINPFAHVPFGIGKRMCIGRRLAELQLQLTLCWLIRKYEIVATDNDPVETLHLGTLMPSRE 500

  Fly   511 LRLALRPR 518
            |.:|...|
 Frog   501 LPVAFHRR 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sad	NP_650123.1	CYP24A1-like	91..512	CDD:410677	111/438 (25%)
cyp24a1	XP_012808417.2	CYP24A1	84..502	CDD:410738	111/438 (25%)