Protein Alignment sad and cyp27a1

DIOPT Version :10

• Sequence 1: NP_650123.1
• Gene: sad / 44858
• FlyBaseID: FBgn0003312
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_002933986.3
• Gene: cyp27a1 / 100145331
• XenbaseID: XB-GENE-984298
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 479
• Identity: 129/479 - (26%)
• Similarity: 218/479 - (45%)
• Gaps: 69/479 - (14%)

  Fly    78 GGATHLHKYIDARHKQYGPIFRERLGGTQDAVFVSSANLMRGVFQHEGQYPQHPLPDAWTLYNQQ 142
            |...|.|:......|.|||::|..: |....|.::...:::.:.:.||:||.....|.|..:..:
 Frog   105 GYLLHTHELQLIYKKMYGPLWRSEI-GKYKMVNIADPEVLQRLVRQEGKYPMRNKEDVWKAHRDK 168

  Fly   143 HACQRGLFFMEGAEWLHNRRILNRLLLN--------GNLN-----WMDVHIESCTRRMVDQWKRR 194
            .....|.|..||.:|...|..||:.:|.        |.:|     :||        |:.|..|
 Frog   169 RKLAYGPFTEEGHQWYQIRSALNKKMLKPSEAASYAGGINEVVTDFMD--------RLQDMRK-- 223

  Fly   195 TAEAAAIPLAESGEIRSYELPLLEQQLYRWSIEVLCCIMFGTSVLTCPK-IQSSLDYFTQIVHKV 258
                 |.|   ||::    :..|...|||::.|.:..|:|.|.:....| |......|...:..:
 Frog   224 -----ASP---SGDM----VNDLANALYRFAFEGISNIVFETRIGCLDKQIPPETQKFIDSIGYM 276

  Fly   259 FEHSSRLMTFPPRLAQILRLPIWRDFEANVDEVLREGAAIIDHCIRVQEDQRR------PHDEAL 317
            |::|. .:||.|...:.: ||.|..:....|.:...|..:||.  ::.|.|.|      ...|.|
 Frog   277 FKNSV-YVTFLPHWTRGI-LPYWDHYIEGWDNIFDFGKHLIDK--KMSEIQSRLDKGEEVEGEYL 337

  Fly   318 YHRLQAADVPGDMIKRIFVDLVIAAGDTTAFSSQWALFALSKEPRLQQRLAKERAT--------- 373
            .:.|.:|::....:.....:|::|..|||:.:..||::.|:::|.|||.:.:|.::
 Frog   338 TYLLSSANLTMGEVYGSVCELLLAGVDTTSNTLCWAMYHLARDPELQQAVYEEVSSAAPMDRIPV 402

  Fly   374 ----NDSRLMHGLIKESLRLYPVAPFIGRYLPQ-DAQLGGHFIEKDTMVLLSLYTAGRDPSHFEQ 433
                .:..|:.|:|||:||||||.|...|.:.: :.::|.:...|:|:.:||.|...||..:||.
 Frog   403 AEDIPNMPLLRGVIKETLRLYPVIPTNARIVSEKEVEIGEYRFPKNTLFVLSHYAIARDEENFED 467

  Fly   434 PERVLPERWCIGETEQVHKSHGSLPFAIGQRSCIGRRVALKQLHSLLGRCAAQFEMSCLNEMP-- 496
            |.:..|:|| :.:....|....|:||..|.|:|:|:|:|..::|..|.|....||   |...|
 Frog   468 PLKFKPQRW-LRDGGMKHHPFSSIPFGYGVRACLGKRIAELEMHLALSRVIRMFE---LRWDPKG 528

  Fly   497 --VDSVLRMVTVPDRTLRLALRPR 518
              :.|:.|:|..|.:.:.|....|
 Frog   529 EDIKSIARIVLSPSKPVNLQFLER 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sad	NP_650123.1	CYP24A1-like	91..512	CDD:410677	124/458 (27%)
cyp27a1	XP_002933986.3	CYP27A1	118..547	CDD:410739	124/459 (27%)