Protein Alignment ru and RHBDL1

DIOPT Version :10

• Sequence 1: NP_524790.1
• Gene: ru / 44856
• FlyBaseID: FBgn0003295
• Length: 341
• Species: Drosophila melanogaster
• Sequence 2: XP_016879338.1
• Gene: RHBDL1 / 9028
• HGNCID: 10007
• Length: 469
• Species: Homo sapiens
• Alignment Length: 362
• Identity: 100/362 - (27%)
• Similarity: 142/362 - (39%)
• Gaps: 109/362 - (30%)

  Fly     3 LLSGAPSQGRRPKNRPLIGT------VEEGEMPPSTVLQMPPAPL--------SSKSGLVLGVCC 53
            |..|:..|...|:|...||.      |...|:|      :.||.|        |::.|   .||.
Human    71 LAGGSSLQQLDPENTGFIGADTFTGLVHSHELP------LDPAKLDMLVALAQSNEQG---QVCY 126

  Fly    54 DQLMAVQPVQRASGAAATKSNSPDWGNHRAKHHEGSAAPF------------------------- 93
            .:|:.:...:|:|......:|     ..||...:|   |.
Human   127 QELVDLISSKRSSSFKRAIAN-----GQRALPRDG---PLDEPGLGVYKRFVRYVAYEILPCEVD 183

  Fly    94 -KWI--------PPFFIILATLLEVLVFLWVGAD---------PPE--DSLLVYRPDQRLQLWRF 138
             :|.        ||.|:...||.:::|||..||.         .||  .|.|||.|..|.:.|||
Human   184 RRWYFYRHRSCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRF 248

  Fly   139 LSYALLHASWLHLGYNVLTQLLFGVPLELVHGSLRTGVIYMAGVLAGSLGTSVVDSEVFLVGASG 203
            |:|..:|.....||:|.|.||:.|||||:|||.||..::|:||||| .||...:..:|...||..
Human   249 LTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLA-ELGWDEMSLQVAEDGAGL 312

  Fly   204 GVYALLA--AQLASLL-----------LNFGQMRHGVIQLMAVILFVFCDLGYALYSRELAMHQL 255
            ||:.|..  .::|:||           |:....|.|               |...:..:   |..
Human   313 GVHELRGGPGRVAALLPAAARLGPTAQLHGAPGRRG---------------GGGEHGPD---HPA 359

  Fly   256 QTRPSVSYIAHMTGALAGISVGLLLLRQLDGGLRPRP 292
            :.|.:.:....:.|..||:. .|..||:|...||.||
Human   360 ELRGAPAGPVRLVGGAAGLR-HLPALRRLLERLRLRP 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ru	NP_524790.1	Rhomboid	129..283	CDD:426384	52/166 (31%)
RHBDL1	XP_016879338.1	Rhomboid	239..>294	CDD:451297	28/54 (52%)