DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ru and rhbdf1a

DIOPT Version :9

Sequence 1:	NP_524790.1	Gene:	ru / 44856	FlyBaseID:	FBgn0003295	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_005164392.1	Gene:	rhbdf1a / 798402	ZFINID:	ZDB-GENE-040704-75	Length:	893	Species:	Danio rerio

Alignment Length:	167	Identity:	45/167 - (26%)
Similarity:	72/167 - (43%)	Gaps:	31/167 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 PDQRLQLWRFLSYALLHASWLHLGYNVLTQLLFGVPLELVHGSLRTGVIYMAGVLAGSLGTSVVD 193
            |||..:||..|   .|||..||...:|..|:.....||.:.|.||..:||:...:.|:|.
Zfish   688 PDQFYRLWLSL---FLHAGILHCLVSVCFQMTILRDLEKLAGWLRISIIYILSGITGNLA----- 744

  Fly   194 SEVFL-----VGASGGVYALLAAQLASLLLNF---GQMRHGVIQLMAVILFVFCDLGYALYSREL 250
            |.:||     ||.:|..:.:||.....|:.::   .|......:|:.|:||:|   .:.|.
Zfish   745 SAIFLPYRAEVGPAGSQFGILACLFVELIQSWQILAQPWRAFTKLLCVVLFLF---AFGLL---- 802

  Fly   251 AMHQLQTRPSVSYIAHMTGALAGISVGLLLLRQLDGG 287
                    |.:...||::|.::|..:....|..:..|
Zfish   803 --------PWIDNFAHISGFISGFFLSFAFLPYISFG 831

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ru	NP_524790.1	Rhomboid	129..282	CDD:279958	43/160 (27%)
rhbdf1a	XP_005164392.1	Rhomboid_SP	130..347	CDD:289371
		Rhomboid	685..826	CDD:279958	43/160 (27%)
		DUF805	<792..864	CDD:294752	12/55 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X418
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820