DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ru and RHBDF1

DIOPT Version :9

Sequence 1:	NP_524790.1	Gene:	ru / 44856	FlyBaseID:	FBgn0003295	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_006720984.1	Gene:	RHBDF1 / 64285	HGNCID:	20561	Length:	878	Species:	Homo sapiens

Alignment Length:	167	Identity:	43/167 - (25%)
Similarity:	72/167 - (43%)	Gaps:	31/167 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 PDQRLQLWRFLSYALLHASWLHLGYNVLTQLLFGVPLELVHGSLRTGVIYMAGVLAGSLGTSVVD 193
            |||..:||..|   .|||..||...::..|:.....||.:.|..|..:||:...:.|:|.
Human   673 PDQFYRLWLSL---FLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLA----- 729

  Fly   194 SEVFL-----VGASGGVYALLAAQLASLLLNF---GQMRHGVIQLMAVILFVFCDLGYALYSREL 250
            |.:||     ||.:|..:.:||.....|..::   .:......:|:||:||:|.   :.|.
Human   730 SAIFLPYRAEVGPAGSQFGILACLFVELFQSWQILARPWRAFFKLLAVVLFLFT---FGLL---- 787

  Fly   251 AMHQLQTRPSVSYIAHMTGALAGISVGLLLLRQLDGG 287
                    |.:...||::|.::|:.:....|..:..|
Human   788 --------PWIDNFAHISGFISGLFLSFAFLPYISFG 816

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ru	NP_524790.1	Rhomboid	129..282	CDD:279958	41/160 (26%)
RHBDF1	XP_006720984.1	Rhomboid_SP	114..331	CDD:403706
RHBDF1	XP_006720984.1	Rhomboid	670..811	CDD:396315	41/160 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X418
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820