DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ru and stet

DIOPT Version :9

Sequence 1:	NP_524790.1	Gene:	ru / 44856	FlyBaseID:	FBgn0003295	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_788450.1	Gene:	stet / 38169	FlyBaseID:	FBgn0020248	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	241	Identity:	125/241 - (51%)
Similarity:	171/241 - (70%)	Gaps:	22/241 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 PPFFIILATLLEVLVFLWVG-----ADP----PEDSLLVYRPDQRLQLWRFLSYALLHASWLHLG 152
            |||||||.||:|:..|::..     |.|    |.||:.:||||:|.::||||.|.:|||.|||||
  Fly   221 PPFFIILVTLVELGFFVYHSVVTGEAAPRGPIPSDSMFIYRPDKRHEIWRFLFYMVLHAGWLHLG 285

  Fly   153 YNVLTQLLFGVPLELVHGSLRTGVIYMAGVLAGSLGTSVVDSEVFLVGASGGVYALLAAQLASLL 217
            :||..||:||:|||:||||.|...||.:||||||||||:.|.:||||||||||||||||.||::|
  Fly   286 FNVAVQLVFGLPLEMVHGSTRIACIYFSGVLAGSLGTSIFDPDVFLVGASGGVYALLAAHLANVL 350

  Fly   218 LNFGQMRHGVIQLMAVILFVFCDLGYALYSRE-------------LAMHQLQTRPSVSYIAHMTG 269
            ||:.|||:|||:|:.:::||..|.|:|:|:|.             ||:.|.:|..:|||:||:.|
  Fly   351 LNYHQMRYGVIKLLHILVFVSFDFGFAIYARYAGDELQLGSSSEFLAIDQAETAGAVSYVAHLAG 415

  Fly   270 ALAGISVGLLLLRQLDGGLRPRPLRWLALGVWCIFSAFGIAFNLVN 315
            |:||:::|||:|:..:..|..:.|.|:|||.:.....|.||||::|
  Fly   416 AIAGLTIGLLVLKSFEQKLHEQLLWWIALGTYLALVVFAIAFNIMN 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ru	NP_524790.1	Rhomboid	129..282	CDD:279958	94/165 (57%)
stet	NP_788450.1	EFh	<75..115	CDD:298682
		EF-hand_7	91..156	CDD:290234
		Rhomboid	262..428	CDD:279958	94/165 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457248
Domainoid	1	1.000	84	1.000	Domainoid score	I2842
eggNOG	1	0.900	-	-		E1_COG0705
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5174
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D102232at50557
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	1	1.000	-	-		mtm1037
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45840
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.800