DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ru and Rhbdl1

DIOPT Version :9

Sequence 1:	NP_524790.1	Gene:	ru / 44856	FlyBaseID:	FBgn0003295	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_008765759.1	Gene:	Rhbdl1 / 117025	RGDID:	620699	Length:	433	Species:	Rattus norvegicus

Alignment Length:	367	Identity:	113/367 - (30%)
Similarity:	177/367 - (48%)	Gaps:	65/367 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLSGAPSQGRRPKNRPLIGT------VEEGEMP--PSTVLQMPPAPLSSKSGLVLGVCCDQLM-- 57
            ||.....|...|:|...||.      |...|:|  |:.:..:.....|::.|   .||..:|:
  Rat    62 LLQLIQEQQLDPENTGFIGADTFAGLVHSHELPLDPTKLDMLVALAQSNERG---QVCYQELVDL 123

  Fly    58 --AVQPVQRASGAAATKSNSPDWGNHRAKHHEG-----------------------SAAPFKWI- 96
              |:...:|:|......:|     ..||...:|                       .....:|.
  Rat   124 VSAMISSKRSSSFKRAIAN-----GQRALPRDGLLDEPGLGIYKRFVRYVAYEILPCEVDRRWYF 183

  Fly    97 -------PPFFIILATLLEVLVFLWVGAD---------PPE--DSLLVYRPDQRLQLWRFLSYAL 143
                   ||.|:...||.:::|||..||.         .||  .|.|||.|..|.:.||||:|..
  Rat   184 YRHRTCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMF 248

  Fly   144 LHASWLHLGYNVLTQLLFGVPLELVHGSLRTGVIYMAGVLAGSLGTSVVDSEVFLVGASGGVYAL 208
            :|.....||:|.|.||:.|||||:|||.||..::|:||||||||..|:.|....:||.|||||||
  Rat   249 MHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYAL 313

  Fly   209 LAAQLASLLLNFGQMR--HGVIQLMAVILFVFCDLGYALYSRELAMHQLQTRPSVSYIAHMTGAL 271
            .:|.||::::|:..||  :.:::::..::.:..::|.|::.| .:.....:.|..|::||:.||:
  Rat   314 CSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLR-FSPPLPASGPQPSFMAHLAGAV 377

  Fly   272 AGISVGLLLLRQLDGGLRPRPLRWLALGVWCIFSAFGIAFNL 313
            .|:|:||.:||..:..||.:...|:.|..:..|..|.|.:|:
  Rat   378 VGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAIFWNV 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ru	NP_524790.1	Rhomboid	129..282	CDD:279958	63/154 (41%)
Rhbdl1	XP_008765759.1	Rhomboid	234..388	CDD:279958	63/154 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	142	1.000	Domainoid score	I4562
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.780