DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ru and rhbdf1

DIOPT Version :9

Sequence 1:	NP_524790.1	Gene:	ru / 44856	FlyBaseID:	FBgn0003295	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_004917997.1	Gene:	rhbdf1 / 100494777	XenbaseID:	XB-GENE-6083739	Length:	892	Species:	Xenopus tropicalis

Alignment Length:	328	Identity:	66/328 - (20%)
Similarity:	104/328 - (31%)	Gaps:	126/328 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 CC---DQLMAVQPVQRASGAA-------ATKSNSPDWGNHRAKH-----HE--------GSAAPF 93
            ||   |:...:|..:....:.       .|.|::|:..|..|:|     |:        .|..|.
Frog   537 CCVRNDKSGCIQTSEEECSSTLAVWVKWPTHSSTPELANKSARHSGSVCHQDPRFCAEPASVTPH 601

  Fly    94 KW---------------------------------------------------IPPFFIILATLL 107
            :|                                                   :..:|...|||.
Frog   602 EWPDDITKWPVCTKNSDGHFPNHLHMDCVITGRPCCIGTKGRCEITSREYCDFMKGYFHEEATLC 666

  Fly   108 E----------VLVFLWVGADPPEDSLLVYRPDQRLQLWRFLSYALLHASWLHLGYNVLTQLLFG 162
            .          :|.||    ||.       .|||..:||..|   .|||..||...:|..|:...
Frog   667 SQVHCMDDVCGLLPFL----DPE-------FPDQVYRLWLSL---FLHAGVLHCLVSVCFQMTIL 717

  Fly   163 VPLELVHGSLRTGVIYMAGVLAGSLGTSVVDSEVFL-----VGASGGVYALLAAQLASLLLNF-- 220
            ..||.:.|..|..:||:...:.|:|     .|.:||     ||.:|..:.:||.....|..::
Frog   718 RDLEKLAGWHRISIIYILSGITGNL-----TSAIFLPYRAEVGPAGSQFGILACLFVELFQSWQI 777

  Fly   221 -GQMRHGVIQLMAVILFVFCDLGYALYSRELAMHQLQTRPSVSYIAHMTGALAGISVGLLLLRQL 284
             .:......:|.||::|:|.   :.|.            |.:...||..|.::|..:....|..:
Frog   778 LARPWRAFFKLFAVVIFLFT---FGLL------------PWIDNFAHFAGFVSGFFLSFAFLPYI 827

  Fly   285 DGG 287
            ..|
Frog   828 SFG 830

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ru	NP_524790.1	Rhomboid	129..282	CDD:279958	41/160 (26%)
rhbdf1	XP_004917997.1	Rhomboid_SP	127..345	CDD:372211
rhbdf1	XP_004917997.1	Rhomboid	687..827	CDD:366759	42/162 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X418
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010