DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ru and rhbdf2

DIOPT Version :9

Sequence 1:	NP_524790.1	Gene:	ru / 44856	FlyBaseID:	FBgn0003295	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001090673.1	Gene:	rhbdf2 / 100036646	XenbaseID:	XB-GENE-966769	Length:	826	Species:	Xenopus tropicalis

Alignment Length:	185	Identity:	49/185 - (26%)
Similarity:	82/185 - (44%)	Gaps:	35/185 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 PDQRLQLWRFLSYALLHASWLHLGYNVLTQLLFGVPLELVHGSLRTGVIYMAGVLAGSLGTSVVD 193
            |||..:||..|   .|||..:|...:|:.|:.....||.:.|.||..:||:...:.|:|.
Frog   621 PDQFYRLWLSL---FLHAGVIHCCVSVVFQMTVLRDLEKLAGWLRISIIYILSGITGNLA----- 677

  Fly   194 SEVFL-----VGASGGVYALLAAQLASLLLNF---GQMRHGVIQLMAVILFVFCDLGYALYSREL 250
            |.:||     ||.:|..:.|||.....|..::   .:.....::|:.::||:|.   :.|.
Frog   678 SALFLPYRAEVGPAGSQFGLLACLFVELFQSWQILAKPWKAFLKLLGIVLFLFL---FGLL---- 735

  Fly   251 AMHQLQTRPSVSYIAHMTGALAGISVGLLLLRQLDGG----LRPRPLRWLALGVW 301
                    |.:..|||:.|.|:|:.:....|..:..|    .|.|.:..::|.|:
Frog   736 --------PWIDNIAHIFGFLSGLLLSFSFLPYITFGTADKFRKRAMIIISLLVF 782

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ru	NP_524790.1	Rhomboid	129..282	CDD:279958	43/160 (27%)
rhbdf2	NP_001090673.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..38
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	51..78
		Rhomboid_SP	90..287	CDD:372211
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	153..180
		Rhomboid	620..761	CDD:366759	44/162 (27%)
		MFS	746..>803	CDD:391944	9/37 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X418
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920