Protein Alignment rib and ZBTB14

DIOPT Version :10

• Sequence 1: NP_001261085.1
• Gene: rib / 44855
• FlyBaseID: FBgn0003254
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_003400.2
• Gene: ZBTB14 / 7541
• HGNCID: 12860
• Length: 449
• Species: Homo sapiens
• Alignment Length: 541
• Identity: 104/541 - (19%)
• Similarity: 194/541 - (35%)
• Gaps: 123/541 - (22%)

  Fly    14 VGQTYCLRWN--NHQTNLVQILHALHEVGSYVDCSLVVDDEQFQAHRVVLAANSPYFQHILKDVP 76
            :..:..:::|  :|:|..::.|:.....|.:.|.::||:|.:|:|||.||||.|.||:.:.|.:.
Human     5 ISMSETIKYNDDDHKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTYFKKLFKKLE 69

  Fly    77 QDHCSII-LPGVKGFEIAALLQYMYTGETTVTKSQEPEILRTAKELQVKGLYDNLMKFNHASVTP 140
            .|..|:| :..::......:|.||||.:.:|.|.....::.:.:.|.::.| |.|........:|
Human    70 VDSSSVIEIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFL-DKLCSQKRDVSSP 133

  Fly   141 TSSSGAGGAK-------PQNGSASNHSSSVISTSTHISPSAAISSSCSPPPPPQFGYQPGYSHYP 198
            ..::|...:|       |...:|......|                      .:.|.|
Human   134 DENNGQSKSKYCLKINRPIGDAADTQDDDV----------------------EEIGDQ------- 169

  Fly   199 QQQPMSASQIPAGEAPLTPT-QATPHSAASGAGEAGGQWPLTPSAAAAMLNSVYESAADMNPLKR 262
                        .::|...| :.||.|...|.         :|:....:..::.:   ::...:.
Human   170 ------------DDSPSDDTVEGTPPSQEDGK---------SPTTTLRVQEAILK---ELGSEEV 210

  Fly   263 KKLSA----ISSMLLSGNRDTPILRNVLAQANPADSSQPGPMNANGEKTPTHPHQNTQLPAGLGV 323
            :|::.    :.||      :||..:::.:|...|.:...|......|:||             |.
Human   211 RKVNCYGQEVESM------ETPESKDLGSQTPQALTFNDGMSEVKDEQTP-------------GW 256

  Fly   324 SGGERNHSFNGSDYGGDKEPLSPYTDRSFEEETGQSGGKKPEWKRYKQYTRADMMCAIQAVREGM 388
            :....:..|....||..:|.::.       :..|::...:...:::::...||.....:...:|.
Human   257 TTAASDMKFEYLLYGHHREQIAC-------QACGKTFSDEGRLRKHEKLHTADRPFVCEMCTKGF 314

  Fly   389 SALQASRKYGLPSRTLYDKVRKLNITTGRGTHRTP--KRSPPGAESSQGFSYSAAAAAAAHNYGH 451
            :. ||..|..|...|.| |.....: .|:...|.|  |:......:.:.|        |.|....
Human   315 TT-QAHLKEHLKIHTGY-KPYSCEV-CGKSFIRAPDLKKHERVHSNERPF--------ACHMCDK 368

  Fly   452 GHGHHSEVKRDQKVDHVPAHHGMPPTIPPSAAALLDHAFLQQALENR----------GGDMAGRE 506
            ...|.|.:|     ||...|.|..|.:..|.......|...:..||.          ....:..|
Human   369 AFKHKSHLK-----DHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTPSAIQSETE 428

  Fly   507 ALHAMALAAAAHAAANRLSSS 527
            .|.|.|:||.|......::.|
Human   429 QLQAAAMAAEAEQQLETIACS 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rib	NP_001261085.1	BTB_POZ_BAB-like	42..125	CDD:349624	27/83 (33%)
		HTH_psq	373..417	CDD:283007	10/43 (23%)
ZBTB14	NP_003400.2	BTB_POZ_ZBTB14	18..131	CDD:349513	34/113 (30%)
		Nuclear localization signal. /evidence=ECO:0000255	50..66		9/15 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	153..194		11/90 (12%)
		C2H2 Zn finger	279..299	CDD:275368	1/26 (4%)
		SFP1	<303..383	CDD:227516	20/95 (21%)
		C2H2 Zn finger	307..327	CDD:275368	5/20 (25%)
		zf-H2C2_2	319..344	CDD:463886	6/26 (23%)
		C2H2 Zn finger	335..355	CDD:275368	4/20 (20%)
		C2H2 Zn finger	363..383	CDD:275368	6/24 (25%)
		C2H2 Zn finger	391..407	CDD:275368	2/15 (13%)