Protein Alignment rib and Zfp131

DIOPT Version :10

• Sequence 1: NP_001261085.1
• Gene: rib / 44855
• FlyBaseID: FBgn0003254
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001289476.1
• Gene: Zfp131 / 72465
• MGIID: 1919715
• Length: 619
• Species: Mus musculus
• Alignment Length: 697
• Identity: 130/697 - (18%)
• Similarity: 238/697 - (34%)
• Gaps: 213/697 - (30%)

  Fly    19 CLR-WNNHQTNLVQILHALHEVGSYVDCSLVVDDEQFQAHRVVLAANSPYFQHILKDVPQDHCSI 82
            ||: :..|...::..|:...|...:.|.:|:||...|:||:.||||.|.:|....::..|:.. :
Mouse     9 CLQEFPEHHKMILDRLNEQREQDRFTDITLIVDGHHFKAHKAVLAACSKFFYKFFQEFTQEPL-V 72

  Fly    83 ILPGVKGFEIAALLQYMYTGETTVTKSQEP----------EILRTAKELQVKGLYDNLMKFNHAS 137
            .:.||.......|:::.||.:..:...:|.          ::|...|.|:|:.      |.|.|.
Mouse    73 EIEGVSKMAFRHLIEFTYTAKLMIQGEEEANDVWKAAEFLQMLEAIKALEVRN------KENSAP 131

  Fly   138 VTPTSSSGAGGAKPQNGSASNHSSSVISTSTHISPSAAISSSCSPPPPPQFGYQPGYSHYPQQQP 202
            : ..:::|...||.:..:   .:|:||:.|.   |||.     |.|...:.....|......:..
Mouse   132 L-EENTTGKNEAKKRKIA---ETSNVITESL---PSAE-----SEPVEIEVEIAEGTIEVEDEGI 184

  Fly   203 MSASQIPAGEAPLTPTQATPHSAASG------------AGEAGGQWPLTPSAAAAMLNSVYESAA 255
            .:..::.:.:..:...|:|..|..|.            .||:.||              :.|...
Mouse   185 EALEEMASAKQSIKYIQSTGSSDDSALALLADITSKYRQGESKGQ--------------ISEDDC 235

  Fly   256 DMNPLKRK---------KLSAISSML--LSGNRDTPILRNVL--AQANPADSSQPGPMNANG-EK 306
            ..:|:.::         :||.:..:.  ...||...:..:..  .:::..:|.:....|... .:
Mouse   236 ASDPISKQVEGIEIVELQLSHVKDLFHCEKCNRSFKLFYHFKEHMKSHSTESFKCEICNKRYLRE 300

  Fly   307 TPTHPHQNT-QLPAGLGVSGGERNHSFNGSDYGGDKEPLSPYTDRSFE------EETGQSGGKKP 364
            :....|.|. .|..| |||..:|.         |.|..:..|.|:.|:      |...:..|:||
Mouse   301 SAWKQHLNCYHLEEG-GVSKKQRT---------GKKIHICQYCDKQFDHFGHFKEHLRKHTGEKP 355

  Fly   365 -EWKR-YKQYTR-ADMMCAIQAVREGMSALQASRKYGLPSRTLY------------DKVR-KLNI 413
             |... ::::.| :.:.|.:.|.:.|:.|.:..:|       ||            |:.: .|.|
Mouse   356 FECSNCHERFARNSTLKCHLTACQTGVGAKKGRKK-------LYECQVCNSVFNSWDQFKDHLVI 413

  Fly   414 TTG-RGTHRT--PKRSPPGAESSQGFSYSAAAAAAAHNYGH------------------------ 451
            .|| :..|.|  ......|.|..:..|       .|||...
Mouse   414 HTGDKPNHCTLCDLWFMQGNELRRHLS-------DAHNISERIVTEEVLSVETHLQTEPVTSMTI 471

  Fly   452 ----GHGH-------------------HSEVKRDQKVDHVPAHHGMPPTIPPSAAALLDHAFLQQ 493
                |..|                   |.::.:|.:| |.....|:|..:..|        :|:.
Mouse   472 IEQVGKVHVLPLLQVQVDSAQVTVEQVHPDLLQDSQV-HDSQMTGLPEQVQVS--------YLEV 527

  Fly   494 A-LENRGGDMAGREALHAMALAAAAHAAANRLSSSPAEMDQRSNGHGMRSPSPQGRHYPHEQEAM 557
            . ::...|.....|.||           ..|::..|.|:                     :.|.:
Mouse   528 GRIQTEEGTEVHVEELH-----------VERVNQMPVEV---------------------QTELL 560

  Fly   558 DLEMEKHEQNIIKRERDQDEREDADDEEDHEQEHVE----DLSLARK 600
            :.:::.....|:.:|..:....||..||..:.|.:|    :.|.|||
Mouse   561 EADLDHMTPEIMSQEEREPNHADAAMEEHEDAEGLETKPSEYSQARK 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rib	NP_001261085.1	BTB_POZ_BAB-like	42..125	CDD:349624	24/92 (26%)
		HTH_psq	373..417	CDD:283007	13/58 (22%)
Zfp131	NP_001289476.1	BTB_POZ_ZBTB35_ZNF131	16..128	CDD:349530	28/118 (24%)
		Nuclear localization signal 1. /evidence=ECO:0000250	137..148		3/10 (30%)
		COG5048	<262..444	CDD:227381	41/205 (20%)
		C2H2 Zn finger	263..283	CDD:275368	2/19 (11%)
		C2H2 Zn finger	290..311	CDD:275368	3/20 (15%)
		Nuclear localization signal 2. /evidence=ECO:0000250	317..328		5/19 (26%)
		C2H2 Zn finger	330..350	CDD:275368	4/19 (21%)
		zf-H2C2_2	342..367	CDD:463886	5/24 (21%)
		C2H2 Zn finger	358..375	CDD:275368	2/16 (13%)
		C2H2 Zn finger	394..414	CDD:275368	2/19 (11%)
		C2H2 Zn finger	422..439	CDD:275370	3/16 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	574..619		11/34 (32%)